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Sibeprenlimab (Synonyms: VIS-649, VIS649)

Catalog No. T77364 Copy Product Info
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Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody that inhibits APRIL and may be investigated for the prevention and treatment of kidney disease (IgAN).

Sibeprenlimab

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Catalog No. T77364
Synonyms VIS-649, VIS649

Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody that inhibits APRIL and may be investigated for the prevention and treatment of kidney disease (IgAN).

Sibeprenlimab
Cas No. 2382896-07-1
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$198-In Stock
5 mg$619-In Stock
10 mg$987-In Stock
25 mg$1,460-In Stock
50 mg$1,970-In Stock
100 mg$2,660-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody that inhibits APRIL and may be investigated for the prevention and treatment of kidney disease (IgAN).
SynonymsVIS-649, VIS649
Reactivity
Human
Verified Activity
Immobilized Human APRIL/TNFSF13 alpha Protein (Flag & His) (TMPJ-00137) at 1 μg/mL (100 μL/well) can bind Sibeprenlimab. The EC50 is 23.65 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTNFSF13/APRIL/CD256
Chemical Properties
Molecular Weight146.36 kDa
Cas No.2382896-07-1
Antibody Information
IsotypeHuman IgG2 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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