Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CMPF is a microtubule protein inhibitor that can be used to study tumors.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 96.00 | |
5 mg | In stock | $ 395.00 | |
10 mg | In stock | $ 588.00 | |
25 mg | In stock | $ 939.00 | |
50 mg | In stock | $ 1,280.00 | |
100 mg | In stock | $ 1,720.00 |
Description | CMPF is a microtubule protein inhibitor that can be used to study tumors. |
In vitro | CMPF is tightly bound to albumin but only moderately inhibits T4 binding in a direct manner (10-14% at 0.3 mM). However, CMPF effectively displaces competitive T4 binding molecules from albumin, such as acidic drugs and free fatty acids. Therefore, CMPF may indirectly influence T4 binding to albumin by increasing the serum concentration of competitive binding molecules, particularly free fatty acids such as oleic acid.[6] |
In vivo | CMPF is highly albumin-bound and accumulates in the serum of uremic patients to concentrations in excess of 0.2 mM. Its primary effect is to inhibit cellular transport and subsequent deiodination of thyroxine (T4).[5] [6] |
Molecular Weight | 240.25 |
Formula | C12H16O5 |
CAS No. | 86879-39-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMF: 27.0 mg/mL (112.3 mM)
DMSO: 27.0 mg/mL (112.3 mM)
Ethanol: 27.0 mg/mL (112.3 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CMPF 86879-39-2 Cytoskeletal Signaling Microtubule Associated inhibitor inhibit