Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 534.00 | |
500 μg | 5 days | $ 2,140.00 | |
1 mg | 5 days | $ 3,570.00 |
Description | Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. |
Species | Cynomolgus |
Expression System | HEK293 |
Tag | N-His |
Accession Number | A0A2K5VNZ0 |
Synonyms | PSMA, FOLHNAALADase I, FGCP, GCPII, PSMAFGCP, NAALADase I, PSM, NAALAD1, GIG27, FOLH, GCPIImGCP, GCP2, mGCP, NAALAdase, Folate hydrolase 1, FOLH1 |
Construction | Recombinant Cynomolgus PSMA/FOLH1 Protein is expressed from HEK293 with His tag at the N-Terminus. It contains Lys44-Ala750.[Accession |A0A2K5VNZ0] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 80.6 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
Stability & Storage |
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. |
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Please read the User Guide of Recombinant Proteins for more specific information.
PSMA Protein, Cynomolgus, Recombinant (His) PSMA FOLHNAALADase I FGCP GCPII PSMAFGCP NAALAD 1 NAALADase I PSM GCP-2 FOLH 1 GIG-27 NAALAD1 GIG27 FOLH GCP 2 GCPIImGCP GCP2 mGCP NAALAdase NAALAD-1 GIG 27 Folate hydrolase 1 FOLH1 FOLH-1 recombinant recombinant-proteins proteins protein