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IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc)
(Synonyms: LeIF D, Interferon α-D, Interferon α-1/13, Interferon α1, Interferon alpha-D, Interferon alpha-1/13, Interferon alpha 1, IFN-α-1/13, IFN-α-1, IFNα1, IFN-alpha-1/13, IFN-alpha-1, IFNalpha 1, IFNA1, IFN α1, IFN α 1, IFN alpha1) Copy Product InfoSynonyms: LeIF D, Interferon α-D, Interferon α-1/13, Interferon α1, Interferon alpha-D, Interferon alpha-1/13, Interferon alpha 1, IFN-α-1/13, IFN-α-1, IFNα1, IFN-alpha-1/13, IFN-alpha-1, IFNalpha 1, IFNA1, IFN α1, IFN α 1, IFN alpha1
Catalog No. TMPK-00075 Copy Product Info
IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.14 kDa and the accession number is P01562.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $58 | - | In Stock | |
| 10 µg | $92 | - | In Stock | |
| 20 µg | $148 | - | In Stock | |
| 50 µg | $289 | 7-10 days | 7-10 days | |
| 100 µg | $487 | - | In Stock | |
| 200 µg | $883 | 7-10 days | 7-10 days | |
| 500 µg | $1,950 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Human IFN alpha/beta R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human IFN alpha 1, hFc Tag with an affinity constant of 0.12 μM as determined in SPR assay. |
| Description | IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.14 kDa and the accession number is P01562. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | P01562 |
| Construction | Cys24-Glu189 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | LeIF D, Interferon α-D, Interferon α-1/13, Interferon α1, Interferon alpha-D, Interferon alpha-1/13, Interferon alpha 1, IFN-α-1/13, IFN-α-1, IFNα1, IFN-alpha-1/13, IFN-alpha-1, IFNalpha 1, IFNA1, IFN α1, IFN α 1, IFN alpha1 |
| Research Background | IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. |
| Molecular Weight | 46.14 kDa (predicted). Due to glycosylation, the protein migrates to 48-55 kDa based on Tris-Bis PAGE result. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc) chemical structure | IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc) molecular weight
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