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UBP1112

Name: UBP1112
Brand: TargetMol
SKU: T23491
Rating: 4.5 (1 reviews)

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Catalog No. T23491Cas No. 339526-74-8

group III mGlu receptor antagonist

UBP1112

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Catalog No. T23491Cas No. 339526-74-8

group III mGlu receptor antagonist

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Product Introduction

Bioactivity

Description

group III mGlu receptor antagonist

Chemical Properties

Molecular Weight	259.2
Formula	C₁₀H₁₄NO₅P
Cas No.	339526-74-8
Smiles	C(C(O)=O)(C)(N)C1=CC(C)=C(P(=O)(O)O)C=C1
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

1eq. NaOH: 100 mM, Sonication is recommended.

Solution Preparation Table

1eq. NaOH

	1mg	5mg	10mg	50mg
1 mM	3.8580 mL	19.2901 mL	38.5802 mL	192.9012 mL
5 mM	0.7716 mL	3.8580 mL	7.7160 mL	38.5802 mL
10 mM	0.3858 mL	1.9290 mL	3.8580 mL	19.2901 mL
20 mM	0.1929 mL	0.9645 mL	1.9290 mL	9.6451 mL
50 mM	0.0772 mL	0.3858 mL	0.7716 mL	3.8580 mL
100 mM	0.0386 mL	0.1929 mL	0.3858 mL	1.9290 mL

Calculator

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Reconstitution Calculator
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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc