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UBP1112

🥰Excellent
Catalog No. T23491Cas No. 339526-74-8

group III mGlu receptor antagonist

UBP1112

UBP1112

🥰Excellent
Catalog No. T23491Cas No. 339526-74-8
group III mGlu receptor antagonist
TargetMol
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Product Introduction

Bioactivity
Description
group III mGlu receptor antagonist
Chemical Properties
Molecular Weight259.2
FormulaC10H14NO5P
Cas No.339526-74-8
SmilesC(C(O)=O)(C)(N)C1=CC(C)=C(P(=O)(O)O)C=C1
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
1eq. NaOH: 100 mM, Sonication is recommended.
Solution Preparation Table
1eq. NaOH
1mg5mg10mg50mg
1 mM3.8580 mL19.2901 mL38.5802 mL192.9012 mL
5 mM0.7716 mL3.8580 mL7.7160 mL38.5802 mL
10 mM0.3858 mL1.9290 mL3.8580 mL19.2901 mL
20 mM0.1929 mL0.9645 mL1.9290 mL9.6451 mL
50 mM0.0772 mL0.3858 mL0.7716 mL3.8580 mL
100 mM0.0386 mL0.1929 mL0.3858 mL1.9290 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

UBP-1112UBP1112UBP 1112
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