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Anti-Phospho-RAD17 (Ser645) Polyclonal Antibody
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Catalog No. TMAC-03501
Anti-Phospho-RAD17 (Ser645) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RAD17 (Ser645). Anti-Phospho-RAD17 (Ser645) Polyclonal Antibody can be used in WB,ELISA.
Anti-Phospho-RAD17 (Ser645) Polyclonal Antibody
Anti-Phospho-RAD17 (Ser645) Polyclonal Antibody
😃Good
Catalog No. TMAC-03501
Anti-Phospho-RAD17 (Ser645) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RAD17 (Ser645). Anti-Phospho-RAD17 (Ser645) Polyclonal Antibody can be used in WB,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $316 | 7-10 days |
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| Description | Anti-Phospho-RAD17 (Ser645) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RAD17 (Ser645). Anti-Phospho-RAD17 (Ser645) Polyclonal Antibody can be used in WB,ELISA. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Appearance | Liquid |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research Background | RAD17 checkpoint clamp loader component(RAD17) Homo sapiens The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, h |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human RAD17 around the phosphorylation site of Ser645. AA range:621-670 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 77 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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