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Anti-PRSS3 Antibody (6K687)

😃Good
Catalog No. TMAY-02124
Alias TRY4, TRY3, T9, RP11-176F3.3, PRSS4, protease, serine 3, MTG

Anti-PRSS3 Antibody (6K687) is a Rabbit antibody targeting PRSS3. Anti-PRSS3 Antibody (6K687) can be used in ELISA.

Anti-PRSS3 Antibody (6K687)

Anti-PRSS3 Antibody (6K687)

😃Good
Catalog No. TMAY-02124Alias TRY4, TRY3, T9, RP11-176F3.3, PRSS4, protease, serine 3, MTG
Anti-PRSS3 Antibody (6K687) is a Rabbit antibody targeting PRSS3. Anti-PRSS3 Antibody (6K687) can be used in ELISA.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-PRSS3 Antibody (6K687) is a Rabbit antibody targeting PRSS3. Anti-PRSS3 Antibody (6K687) can be used in ELISA.
AliasTRY4, TRY3, T9, RP11-176F3.3, PRSS4, protease, serine 3, MTG
Ig Type
Monoclonal Rabbit IgG
Clone
6K687
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Trypsin-3 / PRSS3 (rh Trypsin-3 / PRSS3; TMPY-01897; P35030-3; Met1-Ser247).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTrypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their inhibitors seems to be important for the development of CP. The trypsin inhibitor-degrading activity qualified PRSS3 as a candidate for a novel CP susceptibility gene. Trypsin-3 / PRSS3 has been implicated as a putative tumor suppressor gene due to its loss of expression, which is correlated with promoter hypermethylation, in esophageal squamous cell carcinoma and gastric adenocarcinoma.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Trypsin-3 / PRSS3 protein (TMPY-01897)
Antigen Species
Human
Biology Area
Serine Proteases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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