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Anti-Phospho-STAT1 (Ser727) Antibody (9T764)
(Synonyms: STAT91, STAT1 (p-Ser727), STAT1 (p-S727), signal transducer and activator of transcription 1, 91kDa, p-STAT1 (Ser727), p-STAT1 (S727), Phospho-STAT1 (S727), ISGF-3, IMD31C, IMD31B, IMD31A, CANDF7) Copy Product Info
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Synonyms: STAT91, STAT1 (p-Ser727), STAT1 (p-S727), signal transducer and activator of transcription 1, 91kDa, p-STAT1 (Ser727), p-STAT1 (S727), Phospho-STAT1 (S727), ISGF-3, IMD31C, IMD31B, IMD31A, CANDF7
Catalog No. TMAH-00969 Copy Product Info
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Anti-Phospho-STAT1 (Ser727) Antibody (9T764) is an antibody targeting Phospho-STAT1 (Ser727). Anti-Phospho-STAT1 (Ser727) Antibody (9T764) can be used in ELISA,IF,IHC,WB.
Anti-Phospho-STAT1
(Ser727) Antibody
(9T764)
(Ser727) Antibody
(9T764)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Phospho-STAT1 (Ser727) Antibody (9T764) is an antibody targeting Phospho-STAT1 (Ser727). Anti-Phospho-STAT1 (Ser727) Antibody (9T764) can be used in ELISA,IF,IHC,WB. |
| Synonyms | STAT91, STAT1 (p-Ser727), STAT1 (p-S727), signal transducer and activator of transcription 1, 91kDa, p-STAT1 (Ser727), p-STAT1 (S727), Phospho-STAT1 (S727), ISGF-3, IMD31C, IMD31B, IMD31A, CANDF7 |
| Ig Type | Rabbit IgG |
| Clone | 9T764 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200; IF:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Phospho-STAT1 (S727) |
| Antigen Species | Human |
| Gene Name | STAT1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Signal Transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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