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Fmoc-Gly-Gly-Phe-OtBu

Name: Fmoc-Gly-Gly-Phe-OtBu
Brand: TargetMol
SKU: T17953
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T17953Cas No. 236426-37-2

Fmoc-Gly-Gly-Phe-OtBu, a cleavable ADC linker, can be utilized in the synthesis of antibody-drug conjugates (ADCs).

Fmoc-Gly-Gly-Phe-OtBu

🥰Excellent

Purity: 99.82%

Catalog No. T17953Cas No. 236426-37-2

Fmoc-Gly-Gly-Phe-OtBu, a cleavable ADC linker, can be utilized in the synthesis of antibody-drug conjugates (ADCs).

Pack Size	Price	Availability
25 mg	$54	In Stock
50 mg	$83	In Stock
100 mg	$138	In Stock
500 mg	$338	In Stock
1 mL x 10 mM (in DMSO)	$34	In Stock

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Batch Information

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Purity:99.82%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

Fmoc-Gly-Gly-Phe-OtBu, a cleavable ADC linker, can be utilized in the synthesis of antibody-drug conjugates (ADCs).

Chemical Properties

Molecular Weight	557.64
Formula	C₃₂H₃₅N₃O₆
Cas No.	236426-37-2
Smiles	CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc12
Relative Density.	1.222 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (358.65 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7933 mL	8.9664 mL	17.9327 mL	89.6636 mL
5 mM	0.3587 mL	1.7933 mL	3.5865 mL	17.9327 mL
10 mM	0.1793 mL	0.8966 mL	1.7933 mL	8.9664 mL
20 mM	0.0897 mL	0.4483 mL	0.8966 mL	4.4832 mL
50 mM	0.0359 mL	0.1793 mL	0.3587 mL	1.7933 mL
100 mM	0.0179 mL	0.0897 mL	0.1793 mL	0.8966 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc