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Anti-Phospho-Syk (Tyr352) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Syk (Tyr352). Anti-Phospho-Syk (Tyr352) Polyclonal Antibody can be used in WB,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $318 | 7-10 days |
Description | Anti-Phospho-Syk (Tyr352) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Syk (Tyr352). Anti-Phospho-Syk (Tyr352) Polyclonal Antibody can be used in WB,ELISA. |
Synonyms | Tyrosine-protein kinase SYK(Spleen tyrosine kinase) [Contains: 72kDa tyrosine-protein kinase SYK, Tyrosine-protein kinase SYK, Tyrosine protein kinase SYK, Syk (p-Y352), Syk (p-Tyr352), Syk, Spleen tyrosine kinase, p-Syk (Y352), p-Syk (Tyr352), p72syk, KSYK, 40 kDa tyrosine-protein kinase SYK |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Western blot analysis of extracts from HuvEc cells (Lane 2) and HepG2 cells (Lane 3), using SYK (Phospho-Tyr352) Antibody TMAC-03927. The lane on the left is treated with antigen-specific peptide. |
Application | |
Recommended Dose | WB: 1:500-1000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Appearance | Liquid |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | Peptide sequence around phosphorylation site of tyrosine 352(S-P-Y(p)-A-D) derived from Human SYK |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 72 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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