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Anti-TRAF6 Polyclonal Antibody 2

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Catalog No. TMAB-01885

Anti-TRAF6 Polyclonal Antibody 2 is a Rabbit antibody targeting TRAF6. Anti-TRAF6 Polyclonal Antibody 2 can be used in WB.

Anti-TRAF6 Polyclonal Antibody 2

Anti-TRAF6 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-01885
Anti-TRAF6 Polyclonal Antibody 2 is a Rabbit antibody targeting TRAF6. Anti-TRAF6 Polyclonal Antibody 2 can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$222 7-10 days
100 μL$372 7-10 days
200 μL$529 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Polyclonal

Application: WB

Reactivity: Rat (predicted:Human,Mouse,Pig,Cow,Horse,Rabbit,Sheep)
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
Sample:
Lane 1: Rat Liver tissue lysates
Lane 2: Rat Kidney tissue lysates
Primary: Anti-TRAF6 (TMAB-01885) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kDa
Observed band size: 60 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Cytoplasm, cell cortex. Nucleus. Lipid droplet (By similarity). Note=Found in the nuclei of some agressive B-cell lymphoma cell lines as well as in the nuclei of both resting and activated T- and B-lymphocytes. Found in punctate nuclear body protein complexes. Ubiquitination may occur in the cytoplasm and sumoylation in the nucleus. RSAD2/viperin recruits it to the lipid droplet (By similarity).
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThe protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human TRAF6
Antigen Species
Human
Gene ID
7189
Uniprot ID
Biology Area
Associated Proteins,TRAF,TNF,TRAF,Associated Proteins,TLR Signaling,SARS Coronavirus,TNF,NFkB Pathway
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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