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1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine

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Catalog No. T205285Cas No. 61599-23-3
Alias 16:1 PE, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance the activities of PP2A and PTP1B in malignant pleural mesothelioma cells. Additionally, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis in NCI-H28 malignant pleural mesothelioma cells.

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine

😃Good
Catalog No. T205285Alias 16:1 PE, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamineCas No. 61599-23-3
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance the activities of PP2A and PTP1B in malignant pleural mesothelioma cells. Additionally, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis in NCI-H28 malignant pleural mesothelioma cells.
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Product Introduction

Bioactivity
Description
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance the activities of PP2A and PTP1B in malignant pleural mesothelioma cells. Additionally, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis in NCI-H28 malignant pleural mesothelioma cells.
In vitro
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 1-100 μM; 24-48 hours) reduces the viability of NCI-H28 cells in a concentration-dependent manner (1-100 μM), with no impact on Met5A (non-malignant mesothelial cells) [1]. Additionally, DPPE (100 μM; 10-60 minutes) tends to attenuate the activity of ERK1/ERK2 [1]. Moreover, DPPE (30-100 μM; 48 hours) significantly increases TUNEL-positive NCI-H28 cells, indicating apoptosis, with minimal effects on Met5A [1].
Synonyms16:1 PE, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine
Chemical Properties
Molecular Weight687.927
FormulaC37H70NO8P
Cas No.61599-23-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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