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1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine
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Catalog No. T205285Cas No. 61599-23-3
Alias 16:1 PE, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance the activities of PP2A and PTP1B in malignant pleural mesothelioma cells. Additionally, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis in NCI-H28 malignant pleural mesothelioma cells.
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine
😃Good
Catalog No. T205285Alias 16:1 PE, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamineCas No. 61599-23-3
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance the activities of PP2A and PTP1B in malignant pleural mesothelioma cells. Additionally, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis in NCI-H28 malignant pleural mesothelioma cells.
| Pack Size | Price | Availability | Quantity |
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| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance the activities of PP2A and PTP1B in malignant pleural mesothelioma cells. Additionally, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis in NCI-H28 malignant pleural mesothelioma cells. |
| In vitro | 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 1-100 μM; 24-48 hours) reduces the viability of NCI-H28 cells in a concentration-dependent manner (1-100 μM), with no impact on Met5A (non-malignant mesothelial cells) [1]. Additionally, DPPE (100 μM; 10-60 minutes) tends to attenuate the activity of ERK1/ERK2 [1]. Moreover, DPPE (30-100 μM; 48 hours) significantly increases TUNEL-positive NCI-H28 cells, indicating apoptosis, with minimal effects on Met5A [1]. |
| Alias | 16:1 PE, 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine |
| Molecular Weight | 687.927 |
| Formula | C37H70NO8P |
| Cas No. | 61599-23-3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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