Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Procainamide (Novocainamide) is a specific and potent DNA methyltransferase 1 ( DNMT1 ) inhibitor. Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmias [1] [2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 30.00 | |
100 mg | In stock | $ 39.00 | |
200 mg | In stock | $ 55.00 | |
500 mg | 6-8 weeks | $ 91.00 |
Description | Procainamide (Novocainamide) is a specific and potent DNA methyltransferase 1 ( DNMT1 ) inhibitor. Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmias [1] [2]. |
In vitro | HCT116, HCT116 DNMT1−/−, and HCT116 DNMT3b−/− cells were treated with PBS, pH 7.4 or 0.5 mM procainamide for 96 h. Procainamide treatment of HCT116 DNMT3b−/− cells decreased m5dC content by 11.5%, but treatment of HCT116 DNMT1−/− cells did not decrease m5dC content. These results suggested that DNMT1 was the intracellular target of procainamide[1]. |
Synonyms | Biocoryl, Novocainamide |
Molecular Weight | 235.33 |
Formula | C13H21N3O |
CAS No. | 51-06-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (191.2 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Procainamide 51-06-9 Chromatin/Epigenetic DNA Methyltransferase Biocoryl Novocainamide inhibitor inhibit