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MOG peptide (35-55), mouse, rat acetate
🥰Excellent
Catalog No. T7657L
Alias Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate, MOG peptide (35-55) , mouse, rat acetate (149635-73-4 Free base)
MOG peptide (35-55), mouse, rat acetate, is a minor component of central nervous system myelin with encephalitogenic activity. It can induce CD4⁺ T cell proliferation and Th1-type immune responses, leading to relapsing-remitting demyelinating disease. It is commonly used to establish experimental autoimmune encephalomyelitis (EAE) models.
MOG peptide (35-55), mouse, rat acetate
🥰Excellent
Purity: 97.88%
Catalog No. T7657LAlias Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate, MOG peptide (35-55) , mouse, rat acetate (149635-73-4 Free base)
MOG peptide (35-55), mouse, rat acetate, is a minor component of central nervous system myelin with encephalitogenic activity. It can induce CD4⁺ T cell proliferation and Th1-type immune responses, leading to relapsing-remitting demyelinating disease. It is commonly used to establish experimental autoimmune encephalomyelitis (EAE) models.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $135 | In Stock | |
| 5 mg | $393 | In Stock | |
| 10 mg | $586 | In Stock | |
| 25 mg | $939 | In Stock | |
| 50 mg | $1,270 | In Stock | |
| 100 mg | $1,720 | In Stock |
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Purity:97.88%
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Product Introduction
Bioactivity
Chemical Properties
| Description | MOG peptide (35-55), mouse, rat acetate, is a minor component of central nervous system myelin with encephalitogenic activity. It can induce CD4⁺ T cell proliferation and Th1-type immune responses, leading to relapsing-remitting demyelinating disease. It is commonly used to establish experimental autoimmune encephalomyelitis (EAE) models. |
| In vitro | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) at concentrations ranging from 0 to 50 μg/mL for 72 hours induces T cell proliferation and triggers the secretion of Th1 cytokines, including TNF-α, IL-10, IFN-γ, IL-4, and IL-5. Moreover, it also enhances the production of IgG.[1] |
| In vivo | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55) (200 μg (0.2 mL); i.p.; once, for 38 d) demonstrates encephalitogenic properties in HLA-DR2 (DRB1*1501) mice[1]. |
| Synonyms | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate, MOG peptide (35-55) , mouse, rat acetate (149635-73-4 Free base) |
| Relative Density. | no data available |
| Sequence | H-MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS-OH |
| Sequence Short | MEVGWYRSPFSRVVHLYRNGK |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: 90.0 mg/mL (34.1 mM), Sonication is recommended. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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