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MOG peptide (35-55), mouse, rat acetate, is a minor component of central nervous system myelin with encephalitogenic activity. It can induce CD4⁺ T cell proliferation and Th1-type immune responses, leading to relapsing-remitting demyelinating disease. It is commonly used to establish experimental autoimmune encephalomyelitis (EAE) models.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $135 | In Stock | In Stock | |
| 5 mg | $393 | In Stock | In Stock | |
| 10 mg | $586 | In Stock | In Stock | |
| 25 mg | $939 | In Stock | In Stock | |
| 50 mg | $1,270 | In Stock | In Stock | |
| 100 mg | $1,720 | - | In Stock |
| Description | MOG peptide (35-55), mouse, rat acetate, is a minor component of central nervous system myelin with encephalitogenic activity. It can induce CD4⁺ T cell proliferation and Th1-type immune responses, leading to relapsing-remitting demyelinating disease. It is commonly used to establish experimental autoimmune encephalomyelitis (EAE) models. |
| In vitro | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) at concentrations ranging from 0 to 50 μg/mL for 72 hours induces T cell proliferation and triggers the secretion of Th1 cytokines, including TNF-α, IL-10, IFN-γ, IL-4, and IL-5. Moreover, it also enhances the production of IgG.[1] |
| In vivo | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55) (200 μg (0.2 mL); i.p.; once, for 38 d) demonstrates encephalitogenic properties in HLA-DR2 (DRB1*1501) mice[1]. |
| Synonyms | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate, MOG peptide (35-55) , mouse, rat acetate (149635-73-4 Free base) |
| Relative Density. | no data available |
| Sequence | H-MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS-OH |
| Sequence Short | MEVGWYRSPFSRVVHLYRNGK |
| Storage | store at low temperature,keep away from moisture | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: 90 mg/mL, Sonication is recommended. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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