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DUSP26 Protein, Human, Recombinant (His & SUMO)

(Synonyms: SKRP3, Novel amplified gene in thyroid anaplastic cancer, NATA1, MKP8, Mitogen-activated protein kinase phosphatase 8 (MAP kinase phosphatase 8;MKP-8), Low-molecular-mass dual-specificity phosphatase 4 (DSP-4;LDP-4), LDP4, DUSP26, DUSP24, Dual specificity protein phosphatase 26, Dual specificity phosphatase SKRP3) Copy Product Info

Synonyms: SKRP3, Novel amplified gene in thyroid anaplastic cancer, NATA1, MKP8, Mitogen-activated protein kinase phosphatase 8 (MAP kinase phosphatase 8;MKP-8), Low-molecular-mass dual-specificity phosphatase 4 (DSP-4;LDP-4), LDP4, DUSP26, DUSP24, Dual specificity protein phosphatase 26, Dual specificity phosphatase SKRP3

Catalog No. TMPH-01251 Copy Product Info
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
DUSP26 Protein, Human, Recombinant (His & SUMO)
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$7520 days20 days
10 µg$11920 days20 days
20 µg$19820 days20 days
50 µg$29720 days20 days
100 µg$42720 days20 days
200 µg$65820 days20 days
500 µg$1,17020 days20 days
1 mg$1,83020 days20 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
Species
Human
Expression System
E. coli
TagN-6xHis-SUMO
Accession NumberQ9BV47
Amino AcidMCPGNWLWASMTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLRQGLEA
Construction1-211 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsSKRP3, Novel amplified gene in thyroid anaplastic cancer, NATA1, MKP8, Mitogen-activated protein kinase phosphatase 8 (MAP kinase phosphatase 8;MKP-8), Low-molecular-mass dual-specificity phosphatase 4 (DSP-4;LDP-4), LDP4, DUSP26, DUSP24, Dual specificity protein phosphatase 26, Dual specificity phosphatase SKRP3
Research Background
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
Chemical Properties
Molecular Weight39.9 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: DUSP26 Protein, Human, Recombinant (His & SUMO) chemical structure | DUSP26 Protein, Human, Recombinant (His & SUMO) molecular weight