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Anti-MAP2K1/MEK2 Antibody (4G763)
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Catalog No. TMAC-02537
Alias PRKMK1, MKK1, MEK 1, MAPKK 1, MAPK/ERK kinase 1, MAP kinase kinase 1, ERK activator kinase 1, EC 2.7.12.2, Dual specificity mitogen-activated protein kinase kinase 1
Anti-MAP2K1/MEK2 Antibody (4G763) is a Rabbit antibody targeting MAP2K1/MEK2. Anti-MAP2K1/MEK2 Antibody (4G763) can be used in ICC/IF,IHC,IP,WB.
Anti-MAP2K1/MEK2 Antibody (4G763)
Anti-MAP2K1/MEK2 Antibody (4G763)
😃Good
Catalog No. TMAC-02537Alias PRKMK1, MKK1, MEK 1, MAPKK 1, MAPK/ERK kinase 1, MAP kinase kinase 1, ERK activator kinase 1, EC 2.7.12.2, Dual specificity mitogen-activated protein kinase kinase 1
Anti-MAP2K1/MEK2 Antibody (4G763) is a Rabbit antibody targeting MAP2K1/MEK2. Anti-MAP2K1/MEK2 Antibody (4G763) can be used in ICC/IF,IHC,IP,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Chemical Properties
| Description | Anti-MAP2K1/MEK2 Antibody (4G763) is a Rabbit antibody targeting MAP2K1/MEK2. Anti-MAP2K1/MEK2 Antibody (4G763) can be used in ICC/IF,IHC,IP,WB. |
| Synonyms | PRKMK1, MKK1, MEK 1, MAPKK 1, MAPK/ERK kinase 1, MAP kinase kinase 1, ERK activator kinase 1, EC 2.7.12.2, Dual specificity mitogen-activated protein kinase kinase 1 |
| Ig Type | IgG |
| Clone | 4G763 |
| Reactivity | Human,Mouse,Rat,zebrafish |
| Verified Activity | 1. Western blot analysis of MEK1/2 on different cell lysates using anti-MEK1/2 antibody at 1/1,000 dilution. Positive control: Lane 1: HepG2, Lane 2: PC12, Lane 3: NIH/3T3. 2. Western blot analysis of MEK1/2 on hybrid fish (crucian-carp) brain tissue lysates using anti-MEK1/2 antibody at 1/500 dilution. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-MEK1/2 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-MEK1/2 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-MEK1/2 antibody. Counter stained with hematoxylin. 6. ICC staining MEK1/2 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining MEK1/2 in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.        |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 44 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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