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Anti-MAP2K1/MEK2 Antibody (4G763) (Synonyms: PRKMK1, MKK1, MEK 1, MAPKK 1, MAPK/ERK kinase 1, MAP kinase ki...)

Catalog No. TMAC-02537 Copy Product Info
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Anti-MAP2K1/MEK2 Antibody (4G763) is a Rabbit antibody targeting MAP2K1/MEK2. Anti-MAP2K1/MEK2 Antibody (4G763) can be used in ICC/IF,IHC,IP,WB.

Anti-MAP2K1/MEK2 Antibody (4G763)

Copy Product Info
🥰Excellent
Catalog No. TMAC-02537
Synonyms PRKMK1, MKK1, MEK 1, MAPKK 1, MAPK/ERK kinase 1, MAP kinase kinase 1, ERK activator kinase 1, EC 2.7.12.2, Dual specificity mitogen-activated protein kinase kinase 1

Anti-MAP2K1/MEK2 Antibody (4G763) is a Rabbit antibody targeting MAP2K1/MEK2. Anti-MAP2K1/MEK2 Antibody (4G763) can be used in ICC/IF,IHC,IP,WB.

Anti-MAP2K1/MEK2 Antibody
(4G763)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-MAP2K1/MEK2 Antibody (4G763) is a Rabbit antibody targeting MAP2K1/MEK2. Anti-MAP2K1/MEK2 Antibody (4G763) can be used in ICC/IF,IHC,IP,WB.
SynonymsPRKMK1, MKK1, MEK 1, MAPKK 1, MAPK/ERK kinase 1, MAP kinase kinase 1, ERK activator kinase 1, EC 2.7.12.2, Dual specificity mitogen-activated protein kinase kinase 1
Ig Type
IgG
Clone
4G763
Reactivity
Human,Mouse,Rat,zebrafish
Verified Activity
1. Western blot analysis of MEK1/2 on different cell lysates using anti-MEK1/2 antibody at 1/1,000 dilution. Positive control: Lane 1: HepG2, Lane 2: PC12, Lane 3: NIH/3T3.
2. Western blot analysis of MEK1/2 on hybrid fish (crucian-carp) brain tissue lysates using anti-MEK1/2 antibody at 1/500 dilution.
3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-MEK1/2 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-MEK1/2 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-MEK1/2 antibody. Counter stained with hematoxylin.
6. ICC staining MEK1/2 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining MEK1/2 in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundA family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 44 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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