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HCGRP-(8-37)

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Catalog No. TP1134Cas No. 119911-68-1
Alias Human α-CGRP (8-37)

Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist

HCGRP-(8-37)

HCGRP-(8-37)

😃Good
Catalog No. TP1134Alias Human α-CGRP (8-37)Cas No. 119911-68-1
Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 μg$1,43035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist
SynonymsHuman α-CGRP (8-37)
Chemical Properties
Molecular Weight3125.59
FormulaC139H230N44O38
Cas No.119911-68-1
SmilesC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@H](C(C)C)N)=O)[C@@H](C)O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)C)=O)=O)CC(C)C)=O)CC(C)C)=O)CO)=O)CCCNC(=N)N)=O)CO)=O)=O)=O)[C@@H](C)C)=O)[C@@H](C)C)=O)CCCCN)=O)CC(N)=O)=O)CC(N)=O)=O)=O)[C@@H](C)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)C)=O)CCCCN)=O)CO)=O)=O)C(C)C)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCC3
Relative Density.no data available
SequenceVal-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe
Sequence ShortVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 20 mg/mL (6.4 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM0.3199 mL1.5997 mL3.1994 mL15.9970 mL
5 mM0.0640 mL0.3199 mL0.6399 mL3.1994 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Human α-CGRPHuman alpha-CGRPHuman a-CGRPHCGRP(837)HCGRP (8 37)HCGRP
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