Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PROTAC BRD4 Degrader-14, a PROTAC (Proteolysis Targeting Chimera) linked by ligands to von Hippel-Lindau and BRD4, exhibits IC50 values of 1.8 nM and 1.7 nM for BRD4 BD1 and BD2, respectively. This compound effectively degrades the BRD4 protein in PC3 prostate cancer cells [1].
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Description | PROTAC BRD4 Degrader-14, a PROTAC (Proteolysis Targeting Chimera) linked by ligands to von Hippel-Lindau and BRD4, exhibits IC50 values of 1.8 nM and 1.7 nM for BRD4 BD1 and BD2, respectively. This compound effectively degrades the BRD4 protein in PC3 prostate cancer cells [1]. |
Molecular Weight | 1150.27 |
Formula | C57H61F2N9O11S2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PROTAC BRD4 Degrader-14 inhibitor inhibit