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PSB-1434

🥰Excellent
Catalog No. T24679Cas No. 1619884-65-9
Alias PSB1434, PSB 1434

PSB-1434 is a selective and competitive monoamine oxidase B inhibitor with IC50 of 1.59 nM, selectivity versus MAO-A>6000-fold.

PSB-1434

PSB-1434

🥰Excellent
Purity: 99.57%
Catalog No. T24679Alias PSB1434, PSB 1434Cas No. 1619884-65-9
PSB-1434 is a selective and competitive monoamine oxidase B inhibitor with IC50 of 1.59 nM, selectivity versus MAO-A>6000-fold.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$83In StockIn Stock
5 mg$196In StockIn Stock
10 mg$297In StockIn Stock
25 mg$488In StockIn Stock
50 mg$698In StockIn Stock
100 mg$967In StockIn Stock
200 mg$1,280In StockIn Stock
1 mL x 10 mM (in DMSO)$186In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.57%
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Product Introduction

Bioactivity
Description
PSB-1434 is a selective and competitive monoamine oxidase B inhibitor with IC50 of 1.59 nM, selectivity versus MAO-A>6000-fold.
Targets&IC50
MAO-B:1.59 nM(human)
SynonymsPSB1434, PSB 1434
Chemical Properties
Molecular Weight273.24
FormulaC14H9F2N3O
Cas No.1619884-65-9
SmilesC(NC1=CC(F)=C(F)C=C1)(=O)C=2C=C3C(=CC2)NN=C3
Relative Density.1.498 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (164.69 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6598 mL18.2989 mL36.5979 mL182.9893 mL
5 mM0.7320 mL3.6598 mL7.3196 mL36.5979 mL
10 mM0.3660 mL1.8299 mL3.6598 mL18.2989 mL
20 mM0.1830 mL0.9149 mL1.8299 mL9.1495 mL
50 mM0.0732 mL0.3660 mL0.7320 mL3.6598 mL
100 mM0.0366 mL0.1830 mL0.3660 mL1.8299 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PSB-1434MAO-B
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