Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-CYP2D6 Antibody (8H168)
😃Good
Catalog No. TMAC-01070
Alias Xenobiotic monooxygenase, P450DB1, P450C2D, P450 DB1, Microsomal monooxygenase, Flavoprotein linked monooxygenase, Debrisoquine 4 hydroxylase, Cytochrome P450 family 2 subfamily D polypeptide 6, Cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 DB1, CYPIID6, CYP2DL1, CYP2D8P2, CYP2D7P2, CYP2D7BP, CYP2D7AP, CYP2D6, CYP2D, CPD6
Anti-CYP2D6 Antibody (8H168) is a Rabbit antibody targeting CYP2D6. Anti-CYP2D6 Antibody (8H168) can be used in WB,ICC/IF,IHC,FCM.
Anti-CYP2D6 Antibody (8H168)
Anti-CYP2D6 Antibody (8H168)
😃Good
Catalog No. TMAC-01070Alias Xenobiotic monooxygenase, P450DB1, P450C2D, P450 DB1, Microsomal monooxygenase, Flavoprotein linked monooxygenase, Debrisoquine 4 hydroxylase, Cytochrome P450 family 2 subfamily D polypeptide 6, Cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 DB1, CYPIID6, CYP2DL1, CYP2D8P2, CYP2D7P2, CYP2D7BP, CYP2D7AP, CYP2D6, CYP2D, CPD6
Anti-CYP2D6 Antibody (8H168) is a Rabbit antibody targeting CYP2D6. Anti-CYP2D6 Antibody (8H168) can be used in WB,ICC/IF,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CYP2D6 Antibody (8H168) is a Rabbit antibody targeting CYP2D6. Anti-CYP2D6 Antibody (8H168) can be used in WB,ICC/IF,IHC,FCM. |
| Synonyms | Xenobiotic monooxygenase, P450DB1, P450C2D, P450 DB1, Microsomal monooxygenase, Flavoprotein linked monooxygenase, Debrisoquine 4 hydroxylase, Cytochrome P450 family 2 subfamily D polypeptide 6, Cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 DB1, CYPIID6, CYP2DL1, CYP2D8P2, CYP2D7P2, CYP2D7BP, CYP2D7AP, CYP2D6, CYP2D, CPD6 |
| Ig Type | IgG |
| Clone | 8H168 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of Cytochrome P450 2D6 on HepG2 cell using anti-Cytochrome P450 2D6 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Cytochrome P450 2D6 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Cytochrome P450 2D6 antibody. Counter stained with hematoxylin. 4. ICC staining Cytochrome P450 2D6 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining Cytochrome P450 2D6 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. Flow cytometric analysis of SW480 cells with Cytochrome P450 2D6 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The P450II family comprises at least five subfamilies, designated A through E by the system of nomenclature recommended by an international committee. The P450IID subfamily comprises at least two genes in the rat, one of which is highly specific for debrisoquine 4-hydroxylase activity. An association of this gene with lung cancer has been found. Enhanced CYP2D6 activity has been related to malignancies of the bladder, liver, pharynx and stomach, and especially to cigarette-smoking-induced lung cancer. The data suggests that enhanced CYP2D6-mediated metabolism of one or more dietary and other environmental agents, to form a reactive intermediate, plays a role in cancer initiation and/or promotion in various tissues. CYP2D6 polymorphism, which is responsible for the variation in metabolism of debrisoquine 4-hydroxylase, is important in the metabolism of more than 30 drugs and environmental chemicals, including as much as 20% of all commonly prescribed drugs. The gene which encodes CYP2D6 maps to human chromosome 22q13.1. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 56 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-CYP2D6 Antibody (8H168) | purchase Anti-CYP2D6 Antibody (8H168) | Anti-CYP2D6 Antibody (8H168) cost | order Anti-CYP2D6 Antibody (8H168) | Anti-CYP2D6 Antibody (8H168) molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.