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Anti-CYP2D6 Antibody (8H168)

(Synonyms: Xenobiotic monooxygenase, P450DB1, P450C2D, P450 DB1, Microsomal monooxygenase, Flavoprotein linked monooxygenase, Debrisoquine 4 hydroxylase, Cytochrome P450 family 2 subfamily D polypeptide 6, Cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 DB1, CYPIID6, CYP2DL1, CYP2D8P2, CYP2D7P2, CYP2D7BP, CYP2D7AP, CYP2D6, CYP2D, CPD6) Copy Product Info
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Synonyms: Xenobiotic monooxygenase, P450DB1, P450C2D, P450 DB1, Microsomal monooxygenase, Flavoprotein linked monooxygenase, Debrisoquine 4 hydroxylase, Cytochrome P450 family 2 subfamily D polypeptide 6, Cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 DB1, CYPIID6, CYP2DL1, CYP2D8P2, CYP2D7P2, CYP2D7BP, CYP2D7AP, CYP2D6, CYP2D, CPD6

Catalog No. TMAC-01070 Copy Product Info
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Anti-CYP2D6 Antibody (8H168) is a Rabbit antibody targeting CYP2D6. Anti-CYP2D6 Antibody (8H168) can be used in FCM,ICC/IF,IHC,WB.
Anti-CYP2D6 Antibody
(8H168)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CYP2D6 Antibody (8H168) is a Rabbit antibody targeting CYP2D6. Anti-CYP2D6 Antibody (8H168) can be used in FCM,ICC/IF,IHC,WB.
SynonymsXenobiotic monooxygenase, P450DB1, P450C2D, P450 DB1, Microsomal monooxygenase, Flavoprotein linked monooxygenase, Debrisoquine 4 hydroxylase, Cytochrome P450 family 2 subfamily D polypeptide 6, Cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 DB1, CYPIID6, CYP2DL1, CYP2D8P2, CYP2D7P2, CYP2D7BP, CYP2D7AP, CYP2D6, CYP2D, CPD6
Ig Type
IgG
Clone
8H168
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe P450II family comprises at least five subfamilies, designated A through E by the system of nomenclature recommended by an international committee. The P450IID subfamily comprises at least two genes in the rat, one of which is highly specific for debrisoquine 4-hydroxylase activity. An association of this gene with lung cancer has been found. Enhanced CYP2D6 activity has been related to malignancies of the bladder, liver, pharynx and stomach, and especially to cigarette-smoking-induced lung cancer. The data suggests that enhanced CYP2D6-mediated metabolism of one or more dietary and other environmental agents, to form a reactive intermediate, plays a role in cancer initiation and/or promotion in various tissues. CYP2D6 polymorphism, which is responsible for the variation in metabolism of debrisoquine 4-hydroxylase, is important in the metabolism of more than 30 drugs and environmental chemicals, including as much as 20% of all commonly prescribed drugs. The gene which encodes CYP2D6 maps to human chromosome 22q13.1.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 56 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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