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Synonyms: Nkrp2, NKR P2, NKLLR, NKG2-D-activating NK receptor, NKG2-D type II integral membrane protein, NKG2-D isoform b, NKG2D, NKG2 D type II integral membrane protein, NKG2 D activating NK receptor, NK lectin-like receptor, NK cell receptor D, natural killer cell group 2D, Klrk1, KLR, Killer cell lectin-like receptor subfamily K, Killer cell lectin like receptor subfamily K member 1, D12S2489E, CD314 antigen, CD314, CD 314
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-NKG2D/CD314 Polyclonal Antibody is a Rabbit antibody targeting NKG2D/CD314. Anti-NKG2D/CD314 Polyclonal Antibody can be used in FCM,WB. |
| Synonyms | Nkrp2, NKR P2, NKLLR, NKG2-D-activating NK receptor, NKG2-D type II integral membrane protein, NKG2-D isoform b, NKG2D, NKG2 D type II integral membrane protein, NKG2 D activating NK receptor, NK lectin-like receptor, NK cell receptor D, natural killer cell group 2D, Klrk1, KLR, Killer cell lectin-like receptor subfamily K, Killer cell lectin like receptor subfamily K member 1, D12S2489E, CD314 antigen, CD314, CD 314 |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 2μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Natural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This locus represents naturally occurring read-through transcription between the neighboring KLRC4 (killer cell lectin-like receptor subfamily C, member 4) and KLRK1 (killer cell lectin-like receptor subfamily K, member 1) genes on chromosome 12. The read-through transcript includes an alternate 5' exon and lacks a significant portion of the KLRC4 coding sequence, including the start codon, and it thus encodes the KLRK1 protein. [provided by RefSeq, Dec 2010] |
| Immunogen | KLH conjugated synthetic peptide: rat NKG2D |
| Antigen Species | Rat |
| Gene Name | KLRK1 |
| Gene ID | |
| Protein Name | NKG2-D type II integral membrane protein |
| Uniprot ID | |
| Function | Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. |
| Molecular Weight | Theoretical: 25 kDa. Actual: 26 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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