SECTM1 Protein, Human, Recombinant (hFc)

Name: SECTM1 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPK-00596
Rating: 4.5 (1 reviews)

(Synonyms: SECTM1, K-12) Copy Product Info

Synonyms: SECTM1, K-12

Catalog No. TMPK-00596 Copy Product Info

SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LPS, while at the protein level SECTM1 expression was also shown to be regulated by IFN and LPS. This tight regulation of SECTM1 gene expression and rapid upregulation highlights its relevance in the innate immune response.

SECTM1 Protein, Human, Recombinant (hFc)

Pack Size	Price	USA Stock	Global Stock
5 µg	$39	7-10 days	7-10 days
10 µg	$60	7-10 days	7-10 days
20 µg	$95	7-10 days	7-10 days
50 µg	$182	7-10 days	7-10 days
100 µg	$302	7-10 days	7-10 days
200 µg	$547	7-10 days	7-10 days
500 µg	$1,210	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human CD7, His Tag at 1 μg/mL (100 μL/well) on the plate. Dose response curve for Human SECTM1, hFc Tag with the EC50 of 4.2 ng/mL determined by ELISA (QC Test).Human SECTM1, hFc Tag captured on CM5 Chip via Protein A can bind Mouse CD7, His Tag with an affinity constant of 4.46 μM as determined in SPR assay (Biacore T200).
Description	SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LPS, while at the protein level SECTM1 expression was also shown to be regulated by IFN and LPS. This tight regulation of SECTM1 gene expression and rapid upregulation highlights its relevance in the innate immune response.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	AAH17716
Construction	Gln29-Gly145
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SECTM1, K-12
Research Background	SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LPS, while at the protein level SECTM1 expression was also shown to be regulated by IFN and LPS. This tight regulation of SECTM1 gene expression and rapid upregulation highlights its relevance in the innate immune response.

Chemical Properties

Molecular Weight

39.4 kDa (predicted). Due to glycosylation, the protein migrates to 47-50 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.