TSLPR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 62-88 KDa and the accession number is AAH23788.1.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 184.00 | |
50 μg | 5 days | $ 545.00 | |
500 μg | 5 days | $ 2,070.00 | |
1 mg | 5 days | $ 2,970.00 |
Description | TSLPR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 62-88 KDa and the accession number is AAH23788.1. |
Species | Mouse |
Expression System | HEK293 Cells |
Tag | C-hFc |
Accession Number | AAH23788.1 |
Synonyms | CRLF2, CRL2 cytokine receptor, TSLPR, CRL2, P2RY8/CRLF2 fusion, IL-XR, ILXR, TSLP receptor, Thymic stromal-derived lymphopoietin receptor, Thymic stromal lymphopoietin protein receptor, cytokine receptor-like factor 2 |
Amino Acid | Ala20-Leu233 |
Construction | Ala20-Leu233 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 62-88 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | The cytokine thymic stromal lymphopoietin receptor (TSLPR) is consisting of a common γ receptor–like chain (TSLPR-γ) and a common interleukin 7 (IL-7) Rα chain that belongs to the type 1 cytokine receptor family. Transfection of TSLPR cDNA result in only low affinity binding, while cotransfection of the IL-7Rα chain cDNA shows high affinity binding. TSLP and TSLPR play a critical role in the initiation of allergic diseases in mice. The TSLP R cDNA encodes a transmembrane receptor containing 370 amino acids (aa) with two potential N-linked glycosylation sites and a cytoplasmic domain of 104 aa including a single tyrosine residue. TSLPR can mediate signaling of the signal transducer and activator of transcription 5 (Stat5) by TSLP. TSLP R is broadly expressed in the immune and hematopoietic cells, particularly in hematopoietic progenitors and myeloid cells. |
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TSLPR Protein, Mouse, Recombinant (hFc) CRLF2 CRL2 cytokine receptor TSLPR CRL2 P2RY8/CRLF2 fusion IL-XR ILXR TSLP receptor CRLF-2 CRLF 2 Thymic stromal-derived lymphopoietin receptor CRL 2 CRL-2 Thymic stromal lymphopoietin protein receptor cytokine receptor-like factor 2 recombinant recombinant-proteins proteins protein