Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

PD-1-IN-17

Name: PD-1-IN-17
Brand: TargetMol
SKU: T12377
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T12377Cas No. 1673560-66-1

PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.

PD-1-IN-17

😃Good

Catalog No. T12377Cas No. 1673560-66-1

PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$159	35 days	35 days
5 mg	$717	35 days	35 days
10 mg	$1,270	35 days	35 days

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

Questions

Resource Download

Product Introduction

Bioactivity

Description

PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.

Chemical Properties

Molecular Weight	374.35
Formula	C₁₃H₂₂N₆O₇
Cas No.	1673560-66-1
Relative Density.	1.491 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 112.5 mg/mL (300.5 mM), Sonication is recommended.

H2O: 90 mg/mL (240.42 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6713 mL	13.3565 mL	26.7130 mL	133.5648 mL
5 mM	0.5343 mL	2.6713 mL	5.3426 mL	26.7130 mL
10 mM	0.2671 mL	1.3356 mL	2.6713 mL	13.3565 mL
20 mM	0.1336 mL	0.6678 mL	1.3356 mL	6.6782 mL
50 mM	0.0534 mL	0.2671 mL	0.5343 mL	2.6713 mL
100 mM	0.0267 mL	0.1336 mL	0.2671 mL	1.3356 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc