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Anti-CARD4 Polyclonal Antibody

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Catalog No. TMAB-00278
Alias Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1, Nucleotide binding oligomerization domain containing 1, NOD1, NOD 1, NLRC1, NLRC 1, NLR family CARD domain containing 1, CLR7.1, CLR 7.1, Caspase recruitment domain protein 4, Caspase recruitment domain family member 4, Caspase recruitment domain containing protein 4, Caspase recruitment domain 4, CARD4, CARD 4

Anti-CARD4 Polyclonal Antibody is a Rabbit antibody targeting CARD4. Anti-CARD4 Polyclonal Antibody can be used in WB.

Anti-CARD4 Polyclonal Antibody

Anti-CARD4 Polyclonal Antibody

😃Good
Catalog No. TMAB-00278Alias Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1, Nucleotide binding oligomerization domain containing 1, NOD1, NOD 1, NLRC1, NLRC 1, NLR family CARD domain containing 1, CLR7.1, CLR 7.1, Caspase recruitment domain protein 4, Caspase recruitment domain family member 4, Caspase recruitment domain containing protein 4, Caspase recruitment domain 4, CARD4, CARD 4
Anti-CARD4 Polyclonal Antibody is a Rabbit antibody targeting CARD4. Anti-CARD4 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2207-10 days
100 μL$3727-10 days
200 μL$5277-10 days
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Product Introduction

Bioactivity
Description
Anti-CARD4 Polyclonal Antibody is a Rabbit antibody targeting CARD4. Anti-CARD4 Polyclonal Antibody can be used in WB.
AliasNucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1, Nucleotide binding oligomerization domain containing 1, NOD1, NOD 1, NLRC1, NLRC 1, NLR family CARD domain containing 1, CLR7.1, CLR 7.1, Caspase recruitment domain protein 4, Caspase recruitment domain family member 4, Caspase recruitment domain containing protein 4, Caspase recruitment domain 4, CARD4, CARD 4
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human)
Verified Activity
Sample:
Raw264.7 (Mouse) Cell Lysate at 30 μg
Thymus (Mouse) Lysate at 40 μg
Primary: Anti-CARD4 (TMAB-00278) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 108 kDa
Observed band size: 108 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Basolateral cell membrane. Recruited to the basolateral membrane compartment in polarized epithelial cells.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundEnhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathways activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CARD4
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
CARD Family
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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