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Anti-CARD4 Polyclonal Antibody is a Rabbit antibody targeting CARD4. Anti-CARD4 Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $372 | 7-10 days | |
200 μL | $527 | 7-10 days |
Description | Anti-CARD4 Polyclonal Antibody is a Rabbit antibody targeting CARD4. Anti-CARD4 Polyclonal Antibody can be used in WB. |
Alias | Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1, Nucleotide binding oligomerization domain containing 1, NOD1, NOD 1, NLRC1, NLRC 1, NLR family CARD domain containing 1, CLR7.1, CLR 7.1, Caspase recruitment domain protein 4, Caspase recruitment domain family member 4, Caspase recruitment domain containing protein 4, Caspase recruitment domain 4, CARD4, CARD 4 |
Ig Type | IgG |
Reactivity | Mouse,Rat (predicted:Human) |
Verified Activity | Sample: Raw264.7 (Mouse) Cell Lysate at 30 μg Thymus (Mouse) Lysate at 40 μg Primary: Anti-CARD4 (TMAB-00278) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 108 kDa Observed band size: 108 kDa |
Application | WB |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Cytoplasm. Basolateral cell membrane. Recruited to the basolateral membrane compartment in polarized epithelial cells. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathways activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB. |
Immunogen | KLH conjugated synthetic peptide: human CARD4 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | CARD Family |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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