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Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody 2

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Catalog No. TMAC-02939

Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDKN1A (Thr145). Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.

Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody 2

Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody 2

😃Good
Catalog No. TMAC-02939
Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDKN1A (Thr145). Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2177-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDKN1A (Thr145). Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:10000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research Backgroundcyclin dependent kinase inhibitor 1A(CDKN1A) Homo sapiens This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lac
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human p21 Cip1 around the phosphorylation site of Thr145. AA range:111-160
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 18 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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