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Anti-Integrin beta 3 Antibody (4P677)
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Catalog No. TMAC-02181
Alias PTP, Platelet membrane glycoprotein IIIa, platelet glycoprotein IIIa precursor, Platelet glycoprotein IIIa, Platelet fibrinogen receptor beta subunit, NAIT, ITGB 3, ITG B3, ITB3, Integrin beta-3, Integrin beta chain, β3 precursor, Integrin beta chain beta 3, Integrin beta 3(platelet glycoprotein IIIa antigen CD61), HPA 4, HPA 1, GPIIIa, GP3A, CD61 antigen, CD61, CD 61
Anti-Integrin beta 3 Antibody (4P677) is a Rabbit antibody targeting Integrin beta 3. Anti-Integrin beta 3 Antibody (4P677) can be used in WB,IHC,ICC/IF.
Anti-Integrin beta 3 Antibody (4P677)
Anti-Integrin beta 3 Antibody (4P677)
😃Good
Catalog No. TMAC-02181Alias PTP, Platelet membrane glycoprotein IIIa, platelet glycoprotein IIIa precursor, Platelet glycoprotein IIIa, Platelet fibrinogen receptor beta subunit, NAIT, ITGB 3, ITG B3, ITB3, Integrin beta-3, Integrin beta chain, β3 precursor, Integrin beta chain beta 3, Integrin beta 3(platelet glycoprotein IIIa antigen CD61), HPA 4, HPA 1, GPIIIa, GP3A, CD61 antigen, CD61, CD 61
Anti-Integrin beta 3 Antibody (4P677) is a Rabbit antibody targeting Integrin beta 3. Anti-Integrin beta 3 Antibody (4P677) can be used in WB,IHC,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-Integrin beta 3 Antibody (4P677) is a Rabbit antibody targeting Integrin beta 3. Anti-Integrin beta 3 Antibody (4P677) can be used in WB,IHC,ICC/IF. |
| Synonyms | PTP, Platelet membrane glycoprotein IIIa, platelet glycoprotein IIIa precursor, Platelet glycoprotein IIIa, Platelet fibrinogen receptor beta subunit, NAIT, ITGB 3, ITG B3, ITB3, Integrin beta-3, Integrin beta chain, β3 precursor, Integrin beta chain beta 3, Integrin beta 3(platelet glycoprotein IIIa antigen CD61), HPA 4, HPA 1, GPIIIa, GP3A, CD61 antigen, CD61, CD 61 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Integrin beta 3 on HUVEC cells lysates using anti-Integrin beta 3 antibody at 1/1,000 dilution. 2. Western blotting analysis using Integrin beta 3 Antibody TMAC-02181. 3. TMAC-02181 at 1/100 staining human spleen cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody. 4. TMAC-02181 at 1/100 staining human liver cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody. 5. TMAC-02181 at 1/100 staining human breast cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody. 6. TMAC-02181 at 1/100 staining mouse testis by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody. 7. TMAC-02181 at 1/100 staining mouse colon by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody. 8. ICC staining Integrin beta 3 in HepG2 Cells(red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 87 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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