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N-Phenylbenzylamine

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Catalog No. T0651Cas No. 103-32-2
Alias Benzylaniline, Benzenemethanamine

A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization

N-Phenylbenzylamine

N-Phenylbenzylamine

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Purity: 98.75%
Catalog No. T0651Alias Benzylaniline, BenzenemethanamineCas No. 103-32-2
A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 g$29-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.75%
Appearance:Solid
Color:White
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Product Introduction

N-Phenylbenzylamine AI Summary
N-Phenylbenzylamine shows low bioactivity in the tested assay, with an EC50 value greater than 1000.0 nM for the displacement of biotinylated TN14003 from CXCR4 in MDA-MB-231 cells. Additionally, it exhibits inhibition of acetylcholinesterase (AChE) in Electrophorus electricus (electric eel) with an IC50 value of 13010.0 nM, but shows no significant inhibition of butyrylcholinesterase (BCHE) in Equus caballus (horse) serum, with an IC50 value greater than 100000.0 nM..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization
SynonymsBenzylaniline, Benzenemethanamine
Chemical Properties
Molecular Weight183.25
FormulaC13H13N
Cas No.103-32-2
SmilesC(Nc1ccccc1)c1ccccc1
Relative Density.1.069
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (272.85 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.4570 mL27.2851 mL54.5703 mL272.8513 mL
5 mM1.0914 mL5.4570 mL10.9141 mL54.5703 mL
10 mM0.5457 mL2.7285 mL5.4570 mL27.2851 mL
20 mM0.2729 mL1.3643 mL2.7285 mL13.6426 mL
50 mM0.1091 mL0.5457 mL1.0914 mL5.4570 mL
100 mM0.0546 mL0.2729 mL0.5457 mL2.7285 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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