Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells. AGPS-IN-2i had an inhibitory effect on cancer cell proliferation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 652.00 | |
50 mg | 6-8 weeks | $ 847.00 | |
100 mg | 6-8 weeks | $ 1,280.00 |
Description | AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells. AGPS-IN-2i had an inhibitory effect on cancer cell proliferation. |
In vitro |
AGPS-IN-2i (2i) (500 µM ; 24 h) reduced ether lipids levels and cell migration rate In 231MFP cancer cells.[1] 2i (50、100 µM ; 24 h) specifically impaired epithelial to mesenchymal transition (EMT) by modulating E-cadherin, Snail, and MMP2 expression levels in PC-3 and MDA-MB-231 cancer cells.[1] |
Molecular Weight | 345.34 |
Formula | C18H17F2N3O2 |
CAS No. | 2316782-88-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (65.15 mM)
You can also refer to dose conversion for different animals. More
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AGPS-IN-2i 2316782-88-2 Proteases/Proteasome MMP BMS 986318 BMS986318 inhibitor inhibit