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(±)14(15)-EpETE

Name: (±)14(15)-EpETE
Brand: TargetMol
SKU: T37234
Rating: 4.5 (1 reviews)

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Catalog No. T37234Cas No. 131339-24-7

Alias 14(15)-EpETE

(±)14(15)-EpETE, an eicosatetraenoic acid derivative containing an epoxy group, is an intestinal microbial lipid metabolite that attenuates cisplatin chemotherapy-induced nausea and vomiting in rats by inhibiting Substance P release through targeting GCG/PKA signaling and is commonly used to study inflammation and metabolism.

(±)14(15)-EpETE

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Catalog No. T37234Alias 14(15)-EpETECas No. 131339-24-7

Pack Size	Price	USA Warehouse	Global Warehouse
25 μg	$173	35 days	35 days
50 μg	$323	35 days	35 days
100 μg	$596	35 days	35 days
500 μg	$2,660	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Appearance:Liquid

Color:Transparent

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COA

Product Introduction

Bioactivity

Description	(±)14(15)-EpETE, an eicosatetraenoic acid derivative containing an epoxy group, is an intestinal microbial lipid metabolite that attenuates cisplatin chemotherapy-induced nausea and vomiting in rats by inhibiting Substance P release through targeting GCG/PKA signaling and is commonly used to study inflammation and metabolism.
Synonyms	14(15)-EpETE

Chemical Properties

Molecular Weight	318.45
Formula	C₂₀H₃₀O₃
Cas No.	131339-24-7
Smiles	C(/C=C\C/C=C\C/C=C\CCCC(O)=O)[C@H]1[C@@H](C/C=C\CC)O1

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (31.4 mM), Sonication is recommended.

PBS (pH 7.2): 1 mg/mL (3.14 mM), Sonication is recommended.

Ethanol: 10 mg/mL (31.4 mM), Sonication is recommended.

DMF: 10 mg/mL (31.4 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
1 mM	3.1402 mL	15.7011 mL	31.4021 mL	157.0105 mL

DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
5 mM	0.6280 mL	3.1402 mL	6.2804 mL	31.4021 mL
10 mM	0.3140 mL	1.5701 mL	3.1402 mL	15.7011 mL
20 mM	0.1570 mL	0.7851 mL	1.5701 mL	7.8505 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc