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EpCAM/TROP1 Protein, Mouse, Recombinant (hFc)

Catalog No. TMPJ-00200
Synonyms: 17-1A, 323/A3, TROP1, EGP314, ACSTD1, CD326, EGP-2, MOC31, EGP40, TACST-1, TACSTD1, EpCAM

Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its’ monomer subunit structure interacts with phosphorylated CLDN7. Ep-CAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cells proliferation and differentiation. It also up-regulates the expression of FABP5, MYC and cyclins A and E. The post-translational modification glycosylation at Asn-198 is crucial for protein stability.

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EpCAM/TROP1 Protein, Mouse, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 60.00
50 μg 5 days $ 184.00
500 μg 5 days $ 781.00
1 mg 5 days $ 1,120.00
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Biological Description
Technical Params
Product Properties
Description Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its’ monomer subunit structure interacts with phosphorylated CLDN7. Ep-CAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cells proliferation and differentiation. It also up-regulates the expression of FABP5, MYC and cyclins A and E. The post-translational modification glycosylation at Asn-198 is crucial for protein stability.
Species Mouse
Expression System Human Cells
Tag C-Fc
Accession Number Q99JW5
Synonyms 17-1A, 323/A3, TROP1, EGP314, ACSTD1, CD326, EGP-2, MOC31, EGP40, TACST-1, TACSTD1, EpCAM
Amino Acid Gln24-Thr266
Construction Recombinant Mouse Epithelial Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Gln24-Thr266 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 60-80 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its’ monomer subunit structure interacts with phosphorylated CLDN7. Ep-CAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cells proliferation and differentiation. It also up-regulates the expression of FABP5, MYC and cyclins A and E. The post-translational modification glycosylation at Asn-198 is crucial for protein stability.

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Keywords

EpCAM/TROP1 Protein, Mouse, Recombinant (hFc) TACST1 EGP2 17-1A 323/A3 TROP1 EGP314 EGP 314 TACSTD 1 CD-326 TROP 1 ACSTD1 EGP 2 CD326 TROP-1 ACSTD-1 CD 326 EGP-2 MOC31 EGP-40 TACST 1 EGP40 MOC 31 EGP-314 TACSTD-1 TACST-1 EGP 40 TACSTD1 ACSTD 1 EpCAM MOC-31 recombinant recombinant-proteins proteins protein

 

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