Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Compound PDK0269, as 5-HT3 receptor agonists(3–100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts/episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%). When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited.
Description | Compound PDK0269, as 5-HT3 receptor agonists(3–100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts/episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%). When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited. |
Synonyms | Phenylbiguanide hydrochloride |
Molecular Weight | 213.67 |
Formula | C8H12ClN5 |
CAS No. | 55-57-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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1-Phenylbiguanide HCl 55-57-2 Phenylbiguanide hydrochloride inhibitor inhibit