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Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody

(Synonyms: p-HDAC8 (Ser39), p-HDAC8 (S39), HDAC8 (p-Ser39), HDAC8 (p-S39)) Copy Product Info
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Synonyms: p-HDAC8 (Ser39), p-HDAC8 (S39), HDAC8 (p-Ser39), HDAC8 (p-S39)

Catalog No. TMAC-01791 Copy Product Info
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Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HDAC8 (Ser39). Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody can be used in IF,IHC.

Anti-Phospho-HDAC8
(Ser39) Polyclonal Antibody

Pack SizePriceUSA StockGlobal StockQuantity
50 µL$2167-10 days7-10 days
100 µL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HDAC8 (Ser39). Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody can be used in IF,IHC.
Synonymsp-HDAC8 (Ser39), p-HDAC8 (S39), HDAC8 (p-Ser39), HDAC8 (p-S39)
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using HDAC8 (Phospho-Ser39) Antibody TMAC-01791 (left) or the same antibody preincubated with blocking peptide (right).
2. Immunofluorescence staining of methanol-fixed Hela cells using HDAC8 (Phospho-Ser39) Antibody TMAC-01791.
Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody,Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V) derived from Human HDAC8
Antigen Species
Human
Uniprot ID
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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