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Anti-Phospho-EGF Receptor (Tyr1173) Antibody (9B499) (Synonyms: PIG61, Phospho-EGF Receptor (Y1173), p-EGF Rec...)

Catalog No. TMAY-01621 Copy Product Info
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Anti-Phospho-EGF Receptor (Tyr1173) Antibody (9B499) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr1173). Anti-Phospho-EGF Receptor (Tyr1173) Antibody (9B499) can be used in WB.

Anti-Phospho-EGF Receptor (Tyr1173) Antibody (9B499)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01621
Synonyms PIG61, Phospho-EGF Receptor (Y1173), p-EGF Receptor (Y1173), p-EGF Receptor (Tyr1173), NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB, EGF Receptor (p-Y1173), EGF Receptor (p-Tyr1173)

Anti-Phospho-EGF Receptor (Tyr1173) Antibody (9B499) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr1173). Anti-Phospho-EGF Receptor (Tyr1173) Antibody (9B499) can be used in WB.

Anti-Phospho-EGF Receptor
(Tyr1173) Antibody
(9B499)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$807-10 days7-10 days
100 μL$2337-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-EGF Receptor (Tyr1173) Antibody (9B499) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr1173). Anti-Phospho-EGF Receptor (Tyr1173) Antibody (9B499) can be used in WB.
SynonymsPIG61, Phospho-EGF Receptor (Y1173), p-EGF Receptor (Y1173), p-EGF Receptor (Tyr1173), NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB, EGF Receptor (p-Y1173), EGF Receptor (p-Tyr1173)
Ig Type
Rabbit IgG
Clone
9B499
Reactivity
Human;
Species predicted to react based on 100% sequence homology: cynomolgus
Specificity
Human
Species predicted to react based on 100% sequence homology: cynomolgus
Verified Activity
1. Western blot analysis of extracts from serum-starved Hela, untreated (-) or treated with EGF using Phospho-EGF Receptor (Tyr1173) rabbit monoclonal Antibody at 1:5000 dilution (upper), or Anti-EGFR Antibody, Rabbit Polyclonal at 1:2000 dilution (lower).
2. Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with EGF using Phospho-EGF Receptor (Tyr1173) rabbit monoclonal Antibody at 1:10000 dilution. (Validation Experiment)
Application
Recommended Dose
WB: 1:5000-1:50000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Tyr1173 of the Human Phospho-EGF Receptor.
PurificationProtein A
AppearanceLiquid
Formulation10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
Research BackgroundAs a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: residues around Tyr1173 of the Human Phospho-EGF Receptor
Antigen Species
Human
Biology Area
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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