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Anti-IL-4R Antibody-APC (6U88)
🥰Excellent
Catalog No. TMAY-00775A
Anti-IL-4R Antibody-APC (6U88) is a APC-conjugated Rabbit antibody targeting IL-4R. Anti-IL-4R Antibody-APC (6U88) can be used in FCM.
Anti-IL-4R Antibody-APC (6U88)
Anti-IL-4R Antibody-APC (6U88)
🥰Excellent
Catalog No. TMAY-00775A
Anti-IL-4R Antibody-APC (6U88) is a APC-conjugated Rabbit antibody targeting IL-4R. Anti-IL-4R Antibody-APC (6U88) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL-4R Antibody-APC (6U88) is a APC-conjugated Rabbit antibody targeting IL-4R. Anti-IL-4R Antibody-APC (6U88) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 6U88 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of human IL4R(CD124) expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human IL4R(CD124) and PerCP-Cy5.5-conjugated anti-Human CD19(BD Pharmingen™). The fluorescence histogram were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | 2 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-4R/CD124 (rh IL-4R/CD124; TMPY-01055; NP_000409.1; Met1-His232) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. CD124, also known as the interleukin 4 receptor (IL4R), is a typeⅠ transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4. The membrane-bound form of CD124 can be hydrolyzed to a soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. |
| Conjucates | APC |
| Others Formats | Unconjugated/PE |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human IL-4R/CD124 Protein (TMPY-01055) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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