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Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody (Synonyms: p-ALK (Y1096), p-ALK (Tyr1096), ALK (p-Y1096), ALK ...)

Catalog No. TMAC-00140 Copy Product Info
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Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ALK (Tyr1096). Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody can be used in IHC.

Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-00140
Synonyms p-ALK (Y1096), p-ALK (Tyr1096), ALK (p-Y1096), ALK (p-Tyr1096)

Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ALK (Tyr1096). Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody can be used in IHC.

Anti-Phospho-ALK
(Tyr1096) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2187-10 days7-10 days
100 μL$3187-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ALK (Tyr1096). Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody can be used in IHC.
Synonymsp-ALK (Y1096), p-ALK (Tyr1096), ALK (p-Y1096), ALK (p-Tyr1096)
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human brain tissue, using ALK (Phospho-Tyr1096) antibody TMAC-00140 (left)or the same antibody preincubated with blocking peptide (right).
verifiedActivity
Application
Recommended Dose
IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundThe 2;5 chromosomal translocation is frequently associated with anaplastic large cell lymphomas (ALCLs). The translocation creates a fusion gene consisting of the ALK (anaplastic lymphoma kinase) gene and the nucleophosmin (NPM) gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5. A recent study shows that the product of the NPM-ALK fusion gene is oncogenic. The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 1096 (P-N-Y(p)-C-F) derived from Human ALK
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 176 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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