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Synonyms: Protein CDM, p28, DXS1357E, BCR-associated protein 31, B-cell receptor-associated protein 31, BCAP 31, Bap31, 6C6-AG tumor-associated antigen
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
| Description | Anti-BCAP31 Antibody (3E493) is an antibody targeting BCAP31. Anti-BCAP31 Antibody (3E493) can be used in ELISA,FCM,IF,IHC,WB. |
| Synonyms | Protein CDM, p28, DXS1357E, BCR-associated protein 31, B-cell receptor-associated protein 31, BCAP 31, Bap31, 6C6-AG tumor-associated antigen |
| Ig Type | Rabbit IgG |
| Clone | 3E493 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:2000; IHC:1:50-1:200; IF:1:50-1:200; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. |
| Tissue Specificity | Ubiquitous. Highly expressed in neurons and discrete endocrine cells. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40. In response to ER stress, delocalizes from the ER-mitochondria contact sites and binds BCL2. May be involved in CASP8-mediated apoptosis. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human BCAP31 |
| Antigen Species | Human |
| Gene Name | BCAP31 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cell biology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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