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Anti-PROK2 Polyclonal Antibody (Synonyms: Protein Bv8 homolog, Prokineticin-2, PROK 2, PK2, MIT1, Bv8 homol...)

Catalog No. TMAB-01579 Copy Product Info
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Anti-PROK2 Polyclonal Antibody is a Rabbit antibody targeting PROK2. Anti-PROK2 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.

Anti-PROK2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-01579
Synonyms Protein Bv8 homolog, Prokineticin-2, PROK 2, PK2, MIT1, Bv8 homolog, BV8

Anti-PROK2 Polyclonal Antibody is a Rabbit antibody targeting PROK2. Anti-PROK2 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.

Anti-PROK2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PROK2 Polyclonal Antibody is a Rabbit antibody targeting PROK2. Anti-PROK2 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.
SynonymsProtein Bv8 homolog, Prokineticin-2, PROK 2, PK2, MIT1, Bv8 homolog, BV8
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Pig,Horse)
Verified Activity
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-PROK2/Prokineticin 2 Polyclonal Antibody, Unconjugated (TMAB-01579) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
Tissue SpecificityExpressed in the testis and, at low levels, in the small intestine.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundProkineticin 2 is known to regulate many different biological functions, including neurogenesis, smooth muscle contractility, angiogenesis and circadian rhythm. In serving the latter role, prokineticin 2 functions as an output molecule from the suprachiasmatic nucleus (SCN) of the hypothalamus, that transmits behavioral rhythms, but may also function locally within the SCN to synchronize output. Prokineticin 2 expression is induced by CLOCK and BMAL1 heterodimers and light, and is inhibited by period genes (PER1, PER2 and PER3) and cryptochrome genes (CRY1 and CRY2). Expression is reported in the SCN and among a few other discrete brain areas, including the islands of Calleja, media l preoptic area of the hypothalamus and the shell of the nucleus accumbens as well as in the testis, prostate and, at lower levels, in the small intestine.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PROK2/Prokineticin 2
Antigen Species
Human
Gene Name
PROK2
Gene ID
Protein Name
Prokineticin-2
Uniprot ID
Biology Area
Angiogenic growth factors,Angiogenic Factors,Other Antibodies,Neurogenesis
Function
May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.
Chemical Properties
Molecular WeightTheoretical: 11 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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