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Anti-Podoplanin Antibody (9C226)
😃Good
Catalog No. TMAY-03195
Alias TI1A, T1A-2, T1A2, T1A, podoplanin, PA2.26, OTS8, HT1A-1, GP40, Gp38, GP36, AGGRUS
Anti-Podoplanin Antibody (9C226) is a Rabbit antibody targeting Podoplanin. Anti-Podoplanin Antibody (9C226) can be used in IHC-P.
Anti-Podoplanin Antibody (9C226)
Anti-Podoplanin Antibody (9C226)
😃Good
Catalog No. TMAY-03195Alias TI1A, T1A-2, T1A2, T1A, podoplanin, PA2.26, OTS8, HT1A-1, GP40, Gp38, GP36, AGGRUS
Anti-Podoplanin Antibody (9C226) is a Rabbit antibody targeting Podoplanin. Anti-Podoplanin Antibody (9C226) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $93 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: IHC-P Reactivity: Mouse |
| Alias | TI1A, T1A-2, T1A2, T1A, podoplanin, PA2.26, OTS8, HT1A-1, GP40, Gp38, GP36, AGGRUS |
| Ig Type | Rabbit IgG |
| Clone | 9C226 |
| Reactivity | Mouse |
| Verified Activity | 1. Immunochemical staining of mouse PDPN in mouse kidney with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of mouse PDPN in mouse brain with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:250-1:1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Podoplanin / PDPN (rM Podoplanin / PDPN; TMPY-02659; NP_034459.2; Met1-Lys133). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Podoplanin, also known as PDPN, is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined. Alternatively spliced transcript variants encoding different isoforms have been identified.PDPN is a mucin-type glycoprotein negatively charged by extensive O-glycosylation and a high content of sialic acid, which expresses the adhesive property. It is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. PDPN may contribute to form odontoblastic fiber or function as the anchorage to the tooth development and in proliferating epithelial cells of cervical loop and apical bud. The intensity of podoplanin expression is negatively correlated with the expression of CD34 and factor VIII. Podoplanin would be useful as a diagnostic marker for epithelioid hemangioendothelioma in liver tumors.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse Podoplanin / PDPN Protein (TMPY-02659) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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