Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pomalidomide-amino-PEG5-NH2 is a synthesized conjugate combining the Pomalidomide-based cereblon ligand and a linker utilized in PROTAC technology. It acts as an E3 ligase ligand-linker conjugate.
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Description | Pomalidomide-amino-PEG5-NH2 is a synthesized conjugate combining the Pomalidomide-based cereblon ligand and a linker utilized in PROTAC technology. It acts as an E3 ligase ligand-linker conjugate. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Synonyms | Pomalidomide-amino-PEG5-NH2 |
Molecular Weight | 550.565 |
Formula | C25H34N4O10 |
CAS No. | 2421217-04-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Pomalidomide-amino-PEG5-NH2 2421217-04-9 PomalidomideaminoPEG5NH2 Pomalidomide-amino-PEG-5-NH2 Pomalidomide amino PEG5 NH2 inhibitor inhibit