IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)

Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL-8 effects in gliomas are currently in progress while more-in-depth studies are needed to validate its biomarker role and elucidate the underlying molecular mechanisms.

Pack Size	Availability	Price/USD
100 μg	5 days	$ 487.00
500 μg	5 days	$ 1,950.00
1 mg	5 days	$ 3,250.00

Pack Size

Availability

Price/USD

Quantity

100 μg

5 days

$ 487.00

500 μg

5 days

$ 1,950.00

1 mg

5 days

$ 3,250.00

Description

Species	Cynomolgus
Expression System	HEK293
Tag	C-His
Accession Number	A0A2K5TUL7
Synonyms	GCP/IL-8 protein IV, MDNCF, CXCL8, GCP-1, LUCT, NAF, IL-8, Interleukin-8, MONAP, LYNAP, IL8/NAP1 form I, LECT, NAP-1
Construction	Recombinant Cynomolgus IL-8/CXCL8 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ala23-Pro100.[Accession \|A0A2K5TUL7]
Protein Purity	> 95% as determined by Tris-Bis PAGE
Molecular Weight	The protein has a predicted MW of 10.12 kDa. Due to glycosylation, the protein migrates to 12-14 kDa based on Tris-Bis PAGE result.

Endotoxin	Less than 1EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Stability & Storage	Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background	Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL-8 effects in gliomas are currently in progress while more-in-depth studies are needed to validate its biomarker role and elucidate the underlying molecular mechanisms.