IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)

Catalog No. TMPK-00480

Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL-8 effects in gliomas are currently in progress while more-in-depth studies are needed to validate its biomarker role and elucidate the underlying molecular mechanisms.

IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)

Catalog No. TMPK-00480

Pack Size	Price	Availability
5 μg	$58	7-10 days
10 μg	$92	7-10 days
20 μg	$148	7-10 days
50 μg	$289	7-10 days
100 μg	$487	7-10 days
200 μg	$883	7-10 days
500 μg	$1,950	7-10 days

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Product Information

Biological Activity	Immobilized Cynomolgus IL-8, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-IL-8 Antibody, hFc Tag with the EC50 of 13.0ng/ml determined by ELISA.
Description	Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL-8 effects in gliomas are currently in progress while more-in-depth studies are needed to validate its biomarker role and elucidate the underlying molecular mechanisms.
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	C-His
Accession Number	A0A2K5TUL7
Synonyms	NAP-1,NAF,MONAP,MDNCF,LYNAP,LUCT,LECT,Interleukin-8,IL8/NAP1 form I,IL-8,GCP-1,GCP/IL-8 protein IV,CXCL8
Construction	Ala23-Pro100
Protein Purity	> 95% as determined by Tris-Bis PAGE
Molecular Weight	10.12 kDa (predicted). Due to glycosylation, the protein migrates to 12-14 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL-8 effects in gliomas are currently in progress while more-in-depth studies are needed to validate its biomarker role and elucidate the underlying molecular mechanisms.