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hCAII-IN-8

Name: hCAII-IN-8
Brand: TargetMol
SKU: T67774
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T67774Cas No. 952306-80-8

Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.

hCAII-IN-8

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Purity: 99.73%

Catalog No. T67774Cas No. 952306-80-8

Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.

Pack Size	Price	Availability
5 mg	$37	In Stock
10 mg	$62	In Stock
25 mg	$125	In Stock
50 mg	$186	In Stock
100 mg	$268	In Stock
200 mg	$377	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock

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Batch Information

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Purity:99.73%

Resource Download

COA HPLC LCMS HNMR

Product Introduction

Bioactivity

Description	Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.
Targets&IC50	CA II (human):0.18 μM
In vivo	Compound CDy9 (100 μ M; 24-48 hours) exhibits no cytotoxicity to HEK-293 T cells, with cell viability>90% (versus control) [1].

Chemical Properties

Molecular Weight	336.36
Formula	C₁₅H₁₆N₂O₅S
Cas No.	952306-80-8
Smiles	C(NC1=CC(S(N)(=O)=O)=CC=C1)(=O)C2=CC(OC)=C(OC)C=C2
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (81.76 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9730 mL	14.8650 mL	29.7301 mL	148.6503 mL
5 mM	0.5946 mL	2.9730 mL	5.9460 mL	29.7301 mL
10 mM	0.2973 mL	1.4865 mL	2.9730 mL	14.8650 mL
20 mM	0.1487 mL	0.7433 mL	1.4865 mL	7.4325 mL
50 mM	0.0595 mL	0.2973 mL	0.5946 mL	2.9730 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc