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Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234)
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Catalog No. TMAC-02334
Alias SET8, SET07, SET domain containing (lysine methyltransferase) 8, PR-Set7, KMT5A
Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) is a Rabbit antibody targeting KMT5A/SETD8/PR-Set7. Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) can be used in WB,FCM.
Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234)
Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234)
😃Good
Catalog No. TMAC-02334Alias SET8, SET07, SET domain containing (lysine methyltransferase) 8, PR-Set7, KMT5A
Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) is a Rabbit antibody targeting KMT5A/SETD8/PR-Set7. Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) can be used in WB,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) is a Rabbit antibody targeting KMT5A/SETD8/PR-Set7. Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) can be used in WB,FCM. |
| Synonyms | SET8, SET07, SET domain containing (lysine methyltransferase) 8, PR-Set7, KMT5A |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of KMT5A on different lysates using anti-KMT5A antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse kidney, Lane 2: Mouse liver, Lane 3: 293T, Lane 4: 293. 2. Flow cytometric analysis of 293T cells with KMT5A antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. All monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions , benef playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contribute to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53 / TP53 at 'Lys-382', leading to repress p53 / TP53-target genes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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