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Platelet CD Proteins

Platelets are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot. Platelets have no cell nucleus; they are fragments of cytoplasm derived from the megakaryocytes of the bone marrow or lung, which then enter the circulation. Platelets are found only in mammals, whereas in other vertebrates, thrombocytes circulate as intact mononuclear cells. Quiescent platelets express a large number of surface proteins, including CD9, CD29, CD31, CD36, CD41, CD42a, CD42b, CD61 and gpvi2,3. Some molecules, such as CD41 and CD61, increase their surface levels after platelet activation, while other proteins that are virtually absent on the surface of quiescent platelets, such as CD62P, CD63, CD107a, and CD154, are transferred from intracellular storage to the plasma membrane after activation.

  • CD9 Protein, Human, Recombinant (hFc)
    TMPJ-00111
    CD9, also known as Tspan29, 5H9 antigen, Leukocyte antigen MIC3 (MIC3), Motility-related protein, is a multi-pass membrane protein which belongs to the tetraspanin (TM4SF) family or the transmembrane 4 superfamily. CD9 is a cell surface glycoprotein with 4 hydrophobic domains that is described to complex with integrins and other transmembrane 4 superfamily members. The protein takes part in cellular signal transduction events and thus play a role in the regulation of cell development and activation, growth and motility. Besides, CD9 seems to be a key role in the egg-sperm fusion during the mammalian fertilization processes. CD9 also seems to be a key part in the egg-sperm fusion during mammalian fertilization.
    • $262
    7-10 days
    Size
    QTY
  • SLAMF2 Protein, Mouse, Recombinant (His)
    TMPJ-00128
    CD48 is a GPI-linked protein in the CD2 family of immunoglobulin superfamily proteins. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. Among dendritic cells (DC), CD48 is selectively expressed on circulating myeloid DC and resident bone marrow and thymus DC. CD2, 2B4, and heparan sulfate function as CD48 ligands. CD48 is competent to transduce signals and can also trigger signaling through CD2 or 2B4. CD48 expressed on NK cells is coactivating, whereas CD48 expressed on other cell types inhibits NK cell activation.
    • $116
    7-10 days
    Size
    QTY
  • CD82 Protein, Human, Recombinant (hFc)
    TMPJ-00157
    CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.
    • $157
    7-10 days
    Size
    QTY
  • CD32B Protein, Human, Recombinant (His)
    TMPJ-00192
    FcγRIIB is a low affinity receptor that recognizes the Fc portion of IgG. The human CD32 group consists of FcγRIIA, FcγRIIB, and FcγRIIC proteins that share 94-99% sequence identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic domains. FcγRII protein is expressed on cells of both myeloid and lymphoid lineages as well as on cells of non-hematopoietic origin. FcγRIIB has an intrinsic cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM) and delivers an inhibitory signal upon ligand binding. Ligation of FcγRIIB on B cells down-regulates antibody production and in some circumstances may promote apoptosis. Co-ligation of FcγRIIB on dendritic cells inhibits maturation and blocks cell activation. FcγRIIB may also be a target for monoclonal antibody therapy for malignancies. FcγRIIB plays an important negative-regulating role through modulating the signals from activation receptors.
    • $97
    7-10 days
    Size
    QTY
  • CD36 Protein, Human, Recombinant (hFc)
    TMPJ-00292
    Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal muscle, epithelial cells of the retina, breast, and intestine, smooth muscle cells, erythroid precursors, platelets, megakaryocytes, dendritic cells, monocytes/macrophages, and microglia. As a member of the scavenger receptor family, CD36 is a multiligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands, including long chain fatty acid (LCFA), advanced glycation end products (AGE), thrombospondin-1,oxidized lowdensity lipoproteins (oxLDLs), high density lipoprotein (HDL), phosphatidylserine, apoptotic cells, β amyloid fibrils (fAβ), collagens I and IV, and Plasmodium falciparuminfected erythrocytes. CD36 is required for the antiangiogenic effects of thrombospondin-1 in the corneal neovascularization assay. It plays a role in lipid metabolism and has been identified as a fatty acid translocase necessary for the binding and transport of LCFA in cells and tissues.
    • $110
    7-10 days
    Size
    QTY
  • CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
    TMPJ-00208
    CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is Q08722.
    • $355
    7-10 days
    Size
    QTY
  • CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
    TMPJ-00209
    CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 30-40 KDa and the accession number is Q08722.
    • $355
    7-10 days
    Size
    QTY
  • CD47 Protein, Rhesus macaque, Recombinant (hFc)
    TMPJ-00613
    CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is F7A802.
    • $129
    7-10 days
    Size
    QTY
  • CDH11 Protein, Human, Recombinant (hFc & His)
    TMPJ-01266
    Cadherin-11, also known as OSF-4, Osteoblast cadherin and CDH11, is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.
    • $116
    7-10 days
    Size
    QTY
  • CD99L2 Protein, Human, Recombinant (hFc)
    TMPJ-01239
    CD99L2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is Q8TCZ2.
    • $116
    7-10 days
    Size
    QTY
  • CD99L2 Protein, Human, Recombinant (His)
    TMPJ-01240
    CD99L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-55 KDa and the accession number is Q8TCZ2.
    • $129
    7-10 days
    Size
    QTY
  • PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPK-00420
    Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59.2 kDa and the accession number is P16234.
    • $814
    7-10 days
    Size
    QTY
  • C-MPL Protein, Mouse, Recombinant (aa 26-482, His)
    TMPK-00940
    C-MPL Protein, Mouse, Recombinant (aa 26-482, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.3 kDa and the accession number is Q08351-1.
    • $511
    7-10 days
    Size
    QTY
  • PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
    TMPK-00943
    Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.32 kDa and the accession number is Q0PW86.
    • $487
    7-10 days
    Size
    QTY
  • PDGF R beta/CD140b Protein, Canine, Recombinant (His)
    TMPK-01050
    PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3.
    • $487
    7-10 days
    Size
    QTY
  • CD36 Protein, Cynomolgus, Recombinant (His)
    TMPK-00292
    CD36 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.67 kDa and the accession number is Q4R6B4.
    • $487
    7-10 days
    Size
    QTY
  • GP1BA Protein, Human, Recombinant (His)
    TMPH-01873
    GP1BA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 57.9 kDa and the accession number is BC027955.
    • $198
    20 days
    Size
    QTY
  • ITGB1 Protein, Pig, Recombinant (His & Myc)
    TMPH-03114
    ITGB1 Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.1 kDa and the accession number is Q9GLP0.
    • $360
    20 days
    Size
    QTY
  • CD226 Protein, Rat, Recombinant (His)
    TMPY-00070
    CD226 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is A6K5P0.
    • $357
    7-10 days
    Size
    QTY
  • PDGFRA Protein, Human, Recombinant (His)
    TMPY-01139
    PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1.
    • $386
    In Stock
    Size
    QTY
  • ICAM-1/CD54 Protein, Mouse, Recombinant (His)
    TMPY-01349
    ICAM-1/CD54 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.7 kDa and the accession number is P13597-1.
    • $386
    In Stock
    Size
    QTY
  • CD34 Protein, Mouse, Recombinant (His)
    TMPY-01652
    CD34 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the accession number is Q543Y2.
    • $600
    7-10 days
    Size
    QTY
  • CD99L2 Protein, Mouse, Recombinant (hFc)
    TMPY-01668
    CD99L2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42 kDa and the accession number is Q8BIF0-2.
    • $600
    7-10 days
    Size
    QTY
  • ICAM-2/CD102 Protein, Mouse, Recombinant (hFc)
    TMPY-01799
    ICAM-2/CD102 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50 kDa and the accession number is P35330.
    • $700
    7-10 days
    Size
    QTY
  • E-Cadherin/Cadherin-1 Protein, Mouse, Recombinant (His)
    TMPY-02137
    E-Cadherin/Cadherin-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78 kDa and the accession number is P09803.
    • $600
    7-10 days
    Size
    QTY
  • CD42c Protein, Rat, Recombinant (hFc)
    TMPY-03234
    CD42c Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.1 kDa and the accession number is Q9JJM7.
    • $700
    7-10 days
    Size
    QTY
  • PDGFRB Protein, Rat, Recombinant (His)
    TMPY-03140
    PDGFRB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is Q05030.
    • $398
    7-10 days
    Size
    QTY
  • CD48 Protein, Rat, Recombinant (His)
    TMPY-03089
    CD48 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.9 kDa and the accession number is P10252.
    • $600
    7-10 days
    Size
    QTY
  • P-Selectin Protein, Mouse, Recombinant (hFc)
    TMPY-03415
    P-Selectin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 99.6 kDa and the accession number is Q01102.
    • $600
    7-10 days
    Size
    QTY
  • CD32A Protein, Human, Recombinant (167 His, His)
    TMPY-01968
    CD32A Protein, Human, Recombinant (167 His, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P12318-1.
    • $386
    In Stock
    Size
    QTY
  • CD32A Protein, Rhesus, Recombinant (His)
    TMPY-02080
    CD32A Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.7 kDa and the accession number is H9BMP0.
    • $600
    7-10 days
    Size
    QTY
  • LAMP2 Protein, Mouse, Recombinant (His)
    TMPY-02382
    LAMP2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.6 kDa and the accession number is P17047-1.
    • $600
    7-10 days
    Size
    QTY
  • ICAM-2/CD102 Protein, Mouse, Recombinant
    TMPY-03533
    ICAM-2/CD102 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23.6 kDa and the accession number is P35330.
    • $700
    7-10 days
    Size
    QTY
  • E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc)
    TMPY-03762
    E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.1 kDa and the accession number is P12830-1.
    • $320
    In Stock
    Size
    QTY
  • LAMP2 Protein, Cynomolgus, Recombinant (His)
    TMPY-03685
    LAMP2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is G7Q3L7.
    • $600
    7-10 days
    Size
    QTY
  • CD69 Protein, Mouse, Recombinant (His)
    TMPY-04232
    CD69 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is P37217.
    • $700
    7-10 days
    Size
    QTY
  • P-Selectin Protein, Rhesus, Recombinant (hFc)
    TMPY-04708
    P-Selectin Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 106.8 kDa and the accession number is XP_001094728.1.
    • $700
    7-10 days
    Size
    QTY
  • CD47 Protein, Mouse, Recombinant (His)
    TMPY-04810
    CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the accession number is Q61735-1.
    • $228
    In Stock
    Size
    QTY
  • CD47 Protein, Human, Recombinant
    TMPY-04683
    CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
    • $451
    In Stock
    Size
    QTY
  • CD47 Protein, Mouse, Recombinant (rFc)
    TMPY-04992
    CD47 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 39.9 kDa and the accession number is Q3U967.
    • $904
    7-10 days
    Size
    QTY
  • CD47 Protein, Human, Recombinant, Biotinylated
    TMPY-05191
    CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
    • $197
    In Stock
    Size
    QTY
  • DNAM-1/CD226 Protein, Human, Recombinant (His), Biotinylated
    TMPY-05226
    CD226 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is Q15762.
    • $306
    7-10 days
    Size
    QTY
  • CD47 Protein, Cynomolgus, Rhesus, Recombinant (His)
    TMPY-05343
    CD47 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is XP_005548291.1&NP_001253446.1.
    • $451
    In Stock
    Size
    QTY
  • CD47 Protein, Mouse, Recombinant
    TMPY-05467
    CD47 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.8 kDa and the accession number is E5Q371.
    • $904
    7-10 days
    Size
    QTY
  • PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
    TMPY-05579
    PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.
    • $197
    In Stock
    Size
    QTY
  • CD34 Protein, Human, Recombinant (hFc), Biotinylated
    TMPY-05582
    CD34 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54 kDa and the accession number is P28906-1.
    • $383
    7-10 days
    Size
    QTY
  • E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc), Biotinylated
    TMPY-05656
    E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.1 kDa and the accession number is P12830-1.
    • $306
    7-10 days
    Size
    QTY
  • PDGFRA Protein, Mouse, Recombinant (His)
    TMPY-05787
    PDGFRA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.87 kDa and the accession number is P26618-2.
    • $357
    7-10 days
    Size
    QTY
  • PDGFRA Protein, Mouse, Recombinant (hFc)
    TMPY-05789
    PDGFRA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.15 kDa and the accession number is P26618-2.
    • $357
    7-10 days
    Size
    QTY
  • Nectin-2 Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPY-06383
    Nectin-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 38.80 kDa and the accession number is Q92692-2.
    • $462
    7-10 days
    Size
    QTY