Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Survivin (also known as baculoviral IAP repeat-containing protein 5 (BIRC5)) is a member of the inhibitor of apoptosis (IAP) family that interacts with and inhibits the apoptotic function of several proteins. LLP-3 is a cell-permeable ligand of Survivin that blocks its interaction with Ran, resulting in the induction of apoptosis (IAP) in glioma stem cells (IC50 = 31 μM). It abolishes the growth of glioblastoma multiforme cell in spheres and in tumor slice cultures.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 218.00 |
Description | Survivin (also known as baculoviral IAP repeat-containing protein 5 (BIRC5)) is a member of the inhibitor of apoptosis (IAP) family that interacts with and inhibits the apoptotic function of several proteins. LLP-3 is a cell-permeable ligand of Survivin that blocks its interaction with Ran, resulting in the induction of apoptosis (IAP) in glioma stem cells (IC50 = 31 μM). It abolishes the growth of glioblastoma multiforme cell in spheres and in tumor slice cultures. |
Molecular Weight | 534.99 |
Formula | C32H23ClN2O4 |
CAS No. | 1453835-43-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF:PBS(pH7.2) (1:2): 0.3 mg/mL
DMF: 2 mg/mL
DMSO: 2 mg/mL
You can also refer to dose conversion for different animals. More
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LLP-3 1453835-43-2 LLP3 LLP 3 inhibitor inhibit