Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that combines the Thalidomide-based cereblon ligand with a linker commonly used in PROTAC technology, serving as an E3 ligase recruiter.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | Inquiry | $ 720.00 | |
50 mg | Inquiry | $ 1,134.00 |
Description | Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that combines the Thalidomide-based cereblon ligand with a linker commonly used in PROTAC technology, serving as an E3 ligase recruiter. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Synonyms | Thalidomide-Piperazine-PEG3-NH2 |
Molecular Weight | 517.583 |
Formula | C25H35N5O7 |
CAS No. | 2357113-68-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Thalidomide-Piperazine-PEG3-NH2 2357113-68-7 Thalidomide Piperazine PEG3 NH2 ThalidomidePiperazinePEG3NH2 Thalidomide-Piperazine-PEG-3-NH2 inhibitor inhibit