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POMGNT1 Protein, Human, Recombinant (His)
(Synonyms: UDP-GlcNAc:α-D-Mannoside β-1, UDP-GlcNAc:Alpha-D-Mannoside β-1, UDP-GlcNAc:Alpha-D-Mannoside Beta-1, Protein O-Linked-Mannose β-1, Protein O-Linked-Mannose Beta-1, POMGNT1, MGAT1.2, 2-N-Acetylglucosaminyltransferase I.2, 2-N-Acetylglucosaminyltransferase 1) Copy Product InfoSynonyms: UDP-GlcNAc:α-D-Mannoside β-1, UDP-GlcNAc:Alpha-D-Mannoside β-1, UDP-GlcNAc:Alpha-D-Mannoside Beta-1, Protein O-Linked-Mannose β-1, Protein O-Linked-Mannose Beta-1, POMGNT1, MGAT1.2, 2-N-Acetylglucosaminyltransferase I.2, 2-N-Acetylglucosaminyltransferase 1
Catalog No. TMPJ-01251 Copy Product Info
Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3).
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $112 | 35 days | 35 days | |
| 10 μg | $183 | 35 days | 35 days | |
| 20 μg | $292 | 35 days | 35 days | |
| 50 μg | $545 | 35 days | 35 days | |
| 100 μg | $792 | 35 days | 35 days | |
| 200 μg | $1,150 | 35 days | 35 days | |
| 500 μg | $1,900 | 35 days | 35 days | |
| 1 mg | $2,730 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3). |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-6xHis |
| Accession Number | Q8WZA1 |
| Amino Acid | Leu59-Thr660 |
| Construction | Leu59-Thr660 |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 8.5. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | UDP-GlcNAc:α-D-Mannoside β-1, UDP-GlcNAc:Alpha-D-Mannoside β-1, UDP-GlcNAc:Alpha-D-Mannoside Beta-1, Protein O-Linked-Mannose β-1, Protein O-Linked-Mannose Beta-1, POMGNT1, MGAT1.2, 2-N-Acetylglucosaminyltransferase I.2, 2-N-Acetylglucosaminyltransferase 1 |
| Research Background |
| Molecular Weight | 74 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: POMGNT1 Protein, Human, Recombinant (His) chemical structure | POMGNT1 Protein, Human, Recombinant (His) molecular weight
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