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Anti-Caspase-14 Antibody-FITC (5W237)
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Catalog No. TMAY-02109F
Alias caspase 14, apoptosis-related cysteine peptidase, ARCI12
Anti-Caspase-14 Antibody-FITC (5W237) is a FITC-conjugated Mouse antibody targeting Caspase-14. Anti-Caspase-14 Antibody-FITC (5W237) can be used in FCM.
Anti-Caspase-14 Antibody-FITC (5W237)
Anti-Caspase-14 Antibody-FITC (5W237)
😃Good
Catalog No. TMAY-02109FAlias caspase 14, apoptosis-related cysteine peptidase, ARCI12
Anti-Caspase-14 Antibody-FITC (5W237) is a FITC-conjugated Mouse antibody targeting Caspase-14. Anti-Caspase-14 Antibody-FITC (5W237) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $105 | 7-10 days | |
| 100 T | $211 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Caspase-14 Antibody-FITC (5W237) is a FITC-conjugated Mouse antibody targeting Caspase-14. Anti-Caspase-14 Antibody-FITC (5W237) can be used in FCM. |
| Alias | caspase 14, apoptosis-related cysteine peptidase, ARCI12 |
| Ig Type | Monoclonal Mouse IgG2b |
| Clone | 5W237 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CASP14 expression in HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and stained with FITC Mouse anti-Human CASP14. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Caspase-14 / CASP14 (rh Caspase-14 / CASP14; TMPY-01824; NP_036246.1; Ser2-Gln242) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Caspase 14 was not processed by multiple death stimuli including activation of members of the tumor necrosis factor receptor family and expression of proapaptotic members of the bcl-2 family. Caspase 14 has been described to be processed and activated by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may take part in keratinocyte terminal differentiation, which is essential for the skin barrier. |
| Conjucates | FITC |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human Caspase-14 / CASP14 protein (TMPY-01824) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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