CCL20 Protein, Human, Recombinant (His)

Name: CCL20 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-03935
Price: 74 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: ST38, SCYA20, MIP-3-α, MIP-3-alpha, MIP-3a, MIP3A, LARC, Exodus, CKb4, chemokine (C-C motif) ligand 20) Copy Product Info

Synonyms: ST38, SCYA20, MIP-3-α, MIP-3-alpha, MIP-3a, MIP3A, LARC, Exodus, CKb4, chemokine (C-C motif) ligand 20

Catalog No. TMPY-03935 Copy Product Info

CCL20 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.2 kDa and the accession number is P78556-1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$74	-	In Stock
10 µg	$119	-	In Stock
20 µg	$195	-	In Stock
50 µg	$383	In Stock	In Stock
100 µg	$637	7-10 days	7-10 days
200 µg	$1,060	7-10 days	7-10 days
500 µg	$1,980	7-10 days	7-10 days
1 mg	$3,520	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:SDS-PAGE: > 90%

Appearance:Lyophilized powder

Color:White

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COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CCL20 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.2 kDa and the accession number is P78556-1.
Species	Human
Expression System	E. coli
Tag	N-His
Accession Number	P78556-1
Construction	A DNA sequence encoding the human CCL20 (P78556-1) (Ala27-Met96) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His
Protein Purity	> 90 % as determined by SDS-PAGE
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	ST38, SCYA20, MIP-3-α, MIP-3-alpha, MIP-3a, MIP3A, LARC, Exodus, CKb4, chemokine (C-C motif) ligand 20
Research Background	Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products (including LPS, dsRNA, and PMA). MIP3A / CCL20 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A / CCL20 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A / CCL20 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Chemokine CCL20 was shown to play a role in colorectal cancer (CRC) pathogenesis.

Chemical Properties

Molecular Weight

10.2 kDa (predicted); 10 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.