Stem Cell Differentiation Compound Library

Catalog No. L8000

Library Compound List Excel SDF

Stem cells can differentiate into other types of cells and can divide to produce more of the same type of stem cells. For example, embryonic stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm. Somatic stem cells are thought to be limited to differentiating into different cell types of their tissue of origin. To generate enough specialized cells or tissues that can be used for specific purposes such as tissue regeneration, cell-based therapies, drug screening, or disease models, scientists (must control the cell fate of pluripotent stem cells) are currently working on methods to effectively differentiate stem cells into functional specialized cells. Natural and synthetic small molecules have been shown to be useful chemical tools for controlling and manipulating the fates of cells. For example, Glycogen synthase kinase 3β (GSK-3β) inhibitor could induce differentiation of neural progenitor cells (NPCs). Bone marrow stromal stem cells (BMSSCs) may have potential to differentiate in vitro and in vivo into hepatocytes following the treatment of inhibitor of histone deacetylase and some well-defined cytokines.

Stem Cell Differential Compound Library from TargetMol, a unique collection of 1213 stem cell differentiation signaling targeted compounds, can be used for stem cell research and related drug screening (high throughput and high content screening).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

Request for Quote

If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com

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Product Description

A unique collection of 1213 stem cell differentiation signaling targeted compounds for high throughput and high content screening;
Effective tool for research in regenerative medicine, stem cell differentiation signaling, and drug screening based on stem cells;
Targets include Wnt, GSK-2, Hedgehog, JAK, ROCK, γ-secretase, etc.;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Publications Cited TargetMol Libraries

1. Cell Discovery. 2018, 4(1): 1-12. 2. Experimental Dermatology. 2020. 3. Cell Stem Cell. 2022 Apr 29(4) 545–558. 4. Science Bulletin. 2022. 5. Science Translational Medicine. 2022, 14(656): eabn3231. 6. Science Advances. 2023, 9(9): eade3760. 7. Nature. 2020, 582: 289-293. 8. Nature Biotechnology. 2021, 39(11): 1444-1452. 9. Nature Communications. 2022, 13(1): 1-15..

10. Nature Communications. 2023, 14(1): 1020.. 11. Nature Communications. 2023, 14(1): 2756.. 12. Blood. 2021, 137(11): 1478-1490. 13. Nucleic Acids Research. 2021. 14. Nature Communications. 2023, 14(1): 7574. 15. Advanced Science. 2020, 7(16): 2000925. 16. Angewandte Chemie. 2021. 17. Acta Pharmaceutica Sinica B. 2022. 18. Protein & Cell. 2021, 12(11): 877-888. 19. Bone Research. 2023, 11(1): 54. 20. Pharmacology & Therapeutics. (2021): 107930. 21. Nature Communications. 2021, 12(1): 1-12. 22. Journal of Cell Biology. 2022, 221(5): e202112024.

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Library Composition

Apoptosis (243)

Autophagy (214)

PI3K (150)

Wnt/beta-catenin (89)

JAK (82)

Akt (78)

STAT (75)

mTOR (72)

PPAR (56)

Histone Methyltransferase (54)

p38 MAPK (53)

Endogenous Metabolite (47)

TGF-beta/Smad (47)

ERK (46)

GSK-3 (46)

CDK (42)

NF-κB (41)

AMPK (40)

Antibacterial (38)

ROCK (31)

Hedgehog/Smoothened (31)

Casein Kinase (29)

Gamma-secretase (29)

ALK (29)

Tyrosine Kinases (28)

PKC (28)

DNA-PK (28)

EGFR (27)

IGF-1R (27)

Src (26)

VEGFR (26)

S6 Kinase (23)

p53 (22)

PKA (22)

FLT (21)

Histone Demethylase (21)

Antibiotic (21)

Ferroptosis (19)

COX (18)

ATM/ATR (18)

MEK (18)

Smo (18)

JNK (17)

Parasite (17)

Mitophagy (16)

Reactive Oxygen Species (16)

Beta Amyloid (15)

PARP (15)

Epigenetic Reader Domain (14)

Aurora Kinase (14)

PDGFR (13)

Antifungal (13)

Raf (13)

FGFR (12)

DNA/RNA Synthesis (12)

CXCR (12)

Caspase (12)

DNA Methyltransferase (12)

Potassium Channel (12)

HDAC (12)

HIV Protease (11)

Bcr-Abl (11)

PDE (11)

E1/E2/E3 Enzyme (11)

Sirtuin (11)

Influenza Virus (11)

Beta-Secretase (11)

Dehydrogenase (11)

c-Kit (10)

TNF (10)

PDK (9)

Histone Acetyltransferase (9)

P450 (9)

MAPK (9)

Virus Protease (8)

Adrenergic Receptor (8)

IL Receptor (8)

Interleukin (8)

BACE (8)

Mdm2 (8)

PI4K (7)

Sodium Channel (7)

Ras (7)

HSV (7)

Porcupine (7)

c-RET (7)

c-Met/HGFR (7)

MMP (7)

FAK (7)

5-HT Receptor (7)

Calcium Channel (7)

Retinoid Receptor (6)

Lipoxygenase (6)

ATPase (6)

Mitochondrial Metabolism (6)

YAP (6)

Chk (6)

Aryl Hydrocarbon Receptor (5)

Rho (5)

ROS (5)

Estrogen Receptor/ERR (5)

OCT (5)

Estrogen/progestogen Receptor (5)

IκB/IKK (5)

Phosphatase (5)

Syk (5)

Carbonic Anhydrase (5)

PTEN (4)

Nrf2 (4)

AChE (4)

TLR (4)

BCL (4)

PLK (4)

HIF/HIF Prolyl-Hydroxylase (4)

Adenosine Receptor (4)

Tyrosinase (4)

Histamine Receptor (4)

AChR (4)

c-Fms (4)

Pim (4)

SGK (4)

BTK (4)

SIK (3)

Drug Metabolite (3)

NO Synthase (3)

HSP (3)

Prostaglandin Receptor (3)

Trk receptor (3)

HER (3)

P-gp (3)

MLK (3)

HCV Protease (3)

Antioxidant (3)

DNA Alkylator/Crosslinker (3)

Glucosidase (3)

Microtubule Associated (3)

Proteasome (3)

transporter (3)

Hippo pathway (3)

c-Myc (3)

MAO (3)

CRISPR/Cas9 (3)

Myosin (3)

Topoisomerase (3)

Serine Protease (3)

Serine/threonin kinase (3)

GABA Receptor (3)

Nucleoside Antimetabolite/Analog (3)

LRRK2 (2)

ROS Kinase (2)

HIF (2)

MELK (2)

AhR (2)

Phospholipase (2)

KLF (2)

NADPH-oxidase (2)

S1P Receptor (2)

SARS-CoV (2)

Fatty Acid Synthase (2)

Dopamine Receptor (2)

Integrin (2)

IFNAR (2)

DYRK (2)

ABC (2)

MRP (2)

HBV (2)

FXR (2)

Antiviral (2)

TRP/TRPV Channel (2)

Glucocorticoid Receptor (2)

RIP kinase (2)

GRK (2)

PYK2 (2)

MNK (2)

GluR (2)

CaMK (2)

ACK (2)

PGC-1α (1)

DUB (1)

Anti-infection (1)

Tie-2 (1)

RAAS (1)

PERK (1)

Lipase (1)

BMI-1 (1)

NADPH (1)

cholecystokinin (1)

TAM Receptor (1)

Arginase (1)

Na+/Ca2+ Exchanger (1)

Progesterone Receptor (1)

Amino Acids and Derivatives (1)

BCRP (1)

DHFR (1)

NOS (1)

Adenylyl cyclase (1)

PD-1/PD-L1 (1)

Proton pump (1)

Chloride channel (1)

Kinesin (1)

Monoamine Oxidase (1)

VDA (1)

Cannabinoid Receptor (1)

hCE (1)

Methionine Adenosyltransferase (MAT) (1)

advanced glycation end products (1)

CCR (1)

MAGL (1)

Opioid Receptor (1)

NMDAR (1)

Aromatase (1)

Phosphorylase (1)

Epoxide Hydrolase (1)

UGT (1)

GPR (1)

CSF-1R (1)

Immunology/Inflammation related (1)

Stearoyl-CoA Desaturase (SCD) (1)

RSV (1)

Stemness kinase (1)

Hydroxylase (1)

Glucokinase (1)

NAMPT (1)

cAMP (1)

Cysteine Protease (1)

cell cycle arrest (1)

Serotonin Transporter (1)

DNA (1)

PAI-1 (1)

CaSR (1)

DNA Alkylation (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty