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TargetMol | Compound Library

Stem Cell Differentiation Compound Library

Catalog No. L8000

Stem cells can differentiate into other types of cells and can divide to produce more of the same type of stem cells. For example, embryonic stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm. Somatic stem cells are thought to be limited to differentiating into different cell types of their tissue of origin. To generate enough specialized cells or tissues that can be used for specific purposes such as tissue regeneration, cell-based therapies, drug screening, or disease models, scientists (must control the cell fate of pluripotent stem cells) are currently working on methods to effectively differentiate stem cells into functional specialized cells. Natural and synthetic small molecules have been shown to be useful chemical tools for controlling and manipulating the fates of cells. For example, Glycogen synthase kinase 3β (GSK-3β) inhibitor could induce differentiation of neural progenitor cells (NPCs). Bone marrow stromal stem cells (BMSSCs) may have potential to differentiate in vitro and in vivo into hepatocytes following the treatment of inhibitor of histone deacetylase and some well-defined cytokines.

Stem Cell Differential Compound Library from TargetMol, a unique collection of 1593 stem cell differentiation signaling targeted compounds, can be used for stem cell research and related drug screening (high throughput and high content screening).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8000

Stem Cell Differentiation Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • A unique collection of 1593 stem cell differentiation signaling targeted compounds for high throughput and high content screening;
  • Effective tool for research in regenerative medicine, stem cell differentiation signaling, and drug screening based on stem cells;
  • Targets include Wnt, GSK-2, Hedgehog, JAK, ROCK, γ-secretase, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
EGFR
PI3K
Wnt/beta-catenin
JAK
STAT
GSK-3
Akt
mTOR
TGF-beta/Smad
CDK
p38 MAPK
Histone Methyltransferase
PPAR
ERK
Ras
ROCK
Casein Kinase
Endogenous Metabolite
NF-κB
Gamma-secretase
AMPK
Antibacterial
Potassium Channel
VEGFR
Hedgehog/Smoothened
ALK
Tyrosine Kinases
Src
PKC
FLT
HER
S6 Kinase
IGF-1R
PKA
DNA-PK
Pim
Smo
Raf
COX
p53
ATM/ATR
Antibiotic
YAP
Histone Demethylase
PDGFR
Ferroptosis
PARP
Epigenetic Reader Domain
MEK
JNK
Aurora Kinase
Beta Amyloid
FGFR
Kras
Parasite
Bcr-Abl
Reactive Oxygen Species
Mitophagy
Caspase
DNA/RNA Synthesis
MAPK
TNF
Rho
Antifungal
Cytochromes P450
5-HT Receptor
c-Kit
DNA Methyltransferase
Calcium Channel
PDE
CXCR
Beta-Secretase
HDAC
Dehydrogenase
c-Met/HGFR
E1/E2/E3 Enzyme
IL Receptor
Sirtuin
Histone Acetyltransferase
Influenza Virus
Mdm2
Interleukin
PDK
HIV Protease
BACE
Virus Protease
Adrenergic Receptor
Porcupine
c-RET
DYRK
Serine/threonin kinase
HSV
MMP
Chk
IκB/IKK
PI4K
AChR
Sodium Channel
FAK
Histamine Receptor
Drug Metabolite
Bcl-2 Family
ATPase
HCV Protease
Estrogen/progestogen Receptor
Phosphatase
OCT
Estrogen Receptor/ERR
Aryl Hydrocarbon Receptor
Mitochondrial Metabolism
ROS
Lipoxygenase
TLR
Nrf2
Retinoid Receptor
c-Fms
SGK
Syk
Tyrosinase
Carbonic Anhydrase
Antioxidant
Adenosine Receptor
GTPase
c-Myc
Serine Protease
Topoisomerase
Cholinesterase (ChE)
P-gp
HSP
Trk receptor
Hippo pathway
Microtubule Associated
HIF/HIF Prolyl-Hydroxylase
NO Synthase
BTK
Proteasome
Dopamine Receptor
DNA Alkylator/Crosslinker
Cholecystokinin Receptor
Nucleoside Antimetabolite/Analog
MAO
SIK
RIP kinase
PTEN
GluR
CaMK
Antiviral
transporter
MELK
CRISPR/Cas9
PLK
ROS Kinase
MLK
GPCR
Adenylyl Cyclase
Integrin
Na+/Ca2+ Exchanger
IFNAR
MRP
HBV
AAK1
FXR
LIM Kinase
PYK2
TRP/TRPV Channel
Glucocorticoid Receptor
CSF-1R
Myosin
GRK
NMDAR
ABC Transporter
Glucosidase
Fatty Acid Synthase
CCR
ACK1
cAMP
DUB
Lipid
MNK
Prostaglandin Receptor
SARS-CoV
LRRK2
PAI-1
RSV
KLF
Phospholipase
GABA Receptor
HIF
DAPK
NADPH-oxidase
Melanin-concentrating Hormone Receptor (MCHR)
Advanced Glycation End Products
Chloride channel
Proton pump
Transferase
DHFR
Amino Acids and Derivatives
Arginase
NADPH
RAAS
Lipase
PERK
gp120/CD4
Tie-2
VDA
Progesterone Receptor
CaSR
Photosensitizer
Serotonin Transporter
Cell Cycle Arrest
Cysteine Protease
Glucokinase
NAMPT
Stemness kinase
Annexin A
UGT
Phosphorylase
Antifection
Opioid Receptor
MAGL
DNA Alkylation
Stearoyl-CoA Desaturase (SCD)
Epoxide Hydrolase
Thrombopoietin Receptor
DNA
BCRP
Ephrin Receptor
hCE
Methionine Adenosyltransferase (MAT)
Reverse Transcriptase
Aromatase
Hydroxylase
Cannabinoid Receptor
Anti-infection
BMI-1
IRAK
Sigma receptor
TAM Receptor
AhR
NOD-like Receptor (NLR)
PD-1/PD-L1
Kinesin
S1P Receptor
Monoamine Oxidase
PGC-1α