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TargetMol | Compound Library

Stem Cell Differentiation Compound Library

Catalog No. L8000

Stem cells can differentiate into other types of cells and can divide to produce more of the same type of stem cells. For example, embryonic stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm. Somatic stem cells are thought to be limited to differentiating into different cell types of their tissue of origin. To generate enough specialized cells or tissues that can be used for specific purposes such as tissue regeneration, cell-based therapies, drug screening, or disease models, scientists (must control the cell fate of pluripotent stem cells) are currently working on methods to effectively differentiate stem cells into functional specialized cells. Natural and synthetic small molecules have been shown to be useful chemical tools for controlling and manipulating the fates of cells. For example, Glycogen synthase kinase 3β (GSK-3β) inhibitor could induce differentiation of neural progenitor cells (NPCs). Bone marrow stromal stem cells (BMSSCs) may have potential to differentiate in vitro and in vivo into hepatocytes following the treatment of inhibitor of histone deacetylase and some well-defined cytokines.

Stem Cell Differential Compound Library from TargetMol, a unique collection of 1593 stem cell differentiation signaling targeted compounds, can be used for stem cell research and related drug screening (high throughput and high content screening).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8000

Stem Cell Differentiation Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • A unique collection of 1593 stem cell differentiation signaling targeted compounds for high throughput and high content screening;
  • Effective tool for research in regenerative medicine, stem cell differentiation signaling, and drug screening based on stem cells;
  • Targets include Wnt, GSK-2, Hedgehog, JAK, ROCK, γ-secretase, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
EGFR
Ras
PI3K
Wnt/beta-catenin
JAK
STAT
GSK-3
Akt
mTOR
TGF-beta/Smad
p38 MAPK
Endogenous Metabolite
CDK
Histone Methyltransferase
PPAR
ERK
Antibacterial
ROCK
NF-κB
Casein Kinase
Gamma-secretase
Kras
AMPK
Potassium Channel
Hedgehog/Smoothened
VEGFR
Tyrosine Kinases
ALK
Src
PKC
FLT
Smo
MDM-2/p53
S6 Kinase
IGF-1R
HER
PKA
DNA-PK
Pim
Raf
COX
PARP
Beta Amyloid
ATM/ATR
Antibiotic
p53
Parasite
YAP
Ferroptosis
Histone Demethylase
PDGFR
FGFR
JNK
Reactive Oxygen Species
Epigenetic Reader Domain
MEK
Aurora Kinase
Caspase
Mitophagy
Bcr-Abl
MAPK
TNF
DNA Methyltransferase
DNA/RNA Synthesis
Antifungal
c-Met/HGFR
Rho
Calcium Channel
Cytochromes P450
Histone Acetyltransferase
Influenza Virus
HDAC
5-HT Receptor
c-Kit
HIV Protease
Dehydrogenase
PDE
CXCR
Interleukin
Bcl-2 Family
Virus Protease
E1/E2/E3 Enzyme
Beta-Secretase
Sirtuin
Mdm2
IL Receptor
Porcupine
PDK
DYRK
Adrenergic Receptor
IκB/IKK
c-RET
BACE
Phosphatase
Serine/threonin kinase
Drug Metabolite
HSV
MMP
Chk
PI4K
AChR
Sodium Channel
FAK
ATPase
Histamine Receptor
c-Myc
c-Fms
HIF/HIF Prolyl-Hydroxylase
HCV Protease
Estrogen/progestogen Receptor
OCT
Estrogen Receptor/ERR
Serine Protease
Aryl Hydrocarbon Receptor
Mitochondrial Metabolism
ROS
Lipoxygenase
TLR
Nrf2
Hippo pathway
Retinoid Receptor
SGK
Syk
Anti-infection
Tyrosinase
Microtubule Associated
ROS Kinase
BTK
Carbonic Anhydrase
Antioxidant
Adenosine Receptor
GTPase
Nucleoside Antimetabolite/Analog
Topoisomerase
Cholinesterase (ChE)
PTEN
P-gp
HSP
SARS-CoV
Trk receptor
NO Synthase
GPCR
Proteasome
Dopamine Receptor
Integrin
DNA Alkylator/Crosslinker
Tie-2
Cholecystokinin Receptor
FXR
TRP/TRPV Channel
MAO
SIK
Myosin
RIP kinase
Glucosidase
GluR
CaMK
OXPHOS
Antiviral
transporter
MELK
CRISPR/Cas9
GABA Receptor
PLK
DAPK
MLK
Monoamine Oxidase
Proton pump
Adenylyl Cyclase
Transferase
Na+/Ca2+ Exchanger
IFNAR
PERK
MRP
HBV
AAK1
LIM Kinase
PYK2
Glucocorticoid Receptor
CSF-1R
GRK
NMDAR
ABC Transporter
Antifection
Fatty Acid Synthase
CCR
ACK1
cAMP
DUB
Lipid
Survivin
MNK
Prostaglandin Receptor
LRRK2
PAI-1
RSV
FKBP
KLF
Phospholipase
HIF
NADPH-oxidase
Melanin-concentrating Hormone Receptor (MCHR)
Advanced Glycation End Products
Chloride channel
DHFR
Amino Acids and Derivatives
Y Box Binding Protein 1
Arginase
NADPH
RAAS
Lipase
gp120/CD4
VDA
Progesterone Receptor
CaSR
Photosensitizer
Serotonin Transporter
Cell Cycle Arrest
Cysteine Protease
Glucokinase
NAMPT
Stemness kinase
Prolyl Endopeptidase (PREP)
Annexin A
UGT
Phosphorylase
Na-K-Cl cotransporter
Opioid Receptor
MAGL
DNA Alkylation
Stearoyl-CoA Desaturase (SCD)
Angiotensin-converting Enzyme (ACE)
Epoxide Hydrolase
Thrombopoietin Receptor
DNA
ATP Citrate Lyase
BCRP
Acyltransferase
Ephrin Receptor
hCE
Methionine Adenosyltransferase (MAT)
Reverse Transcriptase
Aromatase
Hydroxylase
Cuproptosis
Cannabinoid Receptor
BMI-1
IRAK
Sigma receptor
TAM Receptor
AhR
NOD-like Receptor (NLR)
PD-1/PD-L1
Kinesin
S1P Receptor
PGC-1α